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Pain Palliation Of Bone Metastases - Production, Quality Control And Dosimetry Of Radiopharmaceuticals

by Iaea

~~53,00€~~ 42,40€ 20% OFF

 Radionuclide therapy using bone targeting radiopharmaceuticals is an effective palliative care option to reduce pain associated with advanced disease with bone metastases. Over the last 20 years, suitable therapeutic radionuclides are more widely available, meaning that the benefits of pain palliation therapy could reach more patients. This publication provides a broad overview on the current status of radiopharmaceuticals for bone pain palliation. It covers production of radionuclides, identification of bone seeking carrier molecules, preparation of stable complexes, in vitro and in vivo evaluations and dosimetry studies which are part of the development of these radiopharmaceuticals for clinical use. Details on production and quality control of the currently available products, provided here will be of use to scientists involved in the development of these radiopharmaceuticals.
ENGLISH

Guidance For Preclinical Studies With Radiopharmaceuticals

by Iaea

~~52,99€~~ 42,39€ 20% OFF

 Preclinical or nonclinical evaluation is an integral part of the development of any drug. The process of developing a new radiopharmaceutical includes rigorous testing before it can be cleared for use in humans. There must be in-depth characterization of its behaviour to assess its safety and suitability for the intended clinical application. This publication provides a baseline guide for preclinical evaluation of radiopharmaceuticals that will give its readers a general review of the requirements of a facility and insight into the various scientific activities that constitute this process. The principles and protocols discussed herein will provide guidelines for biological assessment of candidate compounds, which are consistent with the principles of good laboratory practices to generate valid nonclinical scientific data towards approval for clinical translation. This publication is intended not only for researchers engaged in radiopharmaceutical development, but also for the Member States planning to set up or upgrade facilities for radiopharmaceuticals’ research.
ENGLISH

Copper-64 Radiopharmaceuticals: Production, Quality Control And Clinical Applications

by Iaea

~~47,70€~~ 38,16€ 20% OFF

 Positron emission tomography (PET) is an important clinical tool, and with its longer half-life, copper-64 has several unique attributes that make it a multi-purpose radionuclide with many potential applications. Additionally, copper as a trace element plays a pivotal role in several human metabolic and pathologic diseases and is involved in malignant cells biochemistry pathways. This offers the opportunity for scientists to explore the theranostic capabilities of copper-64. This current publication, arising from an IAEA Coordinated Research Project, describes the biochemical and radiopharmaceutical aspects of copper-64, and its clinical applications, with specific guidelines and methods for the production of copper-64 chloride, peptide and monoclonal antibody radiopharmaceuticals. It is expected to be of use to all professionals involved in the field by specifying ideal production, formulation and quality control methods.
ENGLISH

Cyclotron Produced Radionuclides - Operation And Maintenance Of Gas And Liquid Targets

by International Atomic Energy Agency

31,88€

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OUT OF STOCK OR NOT AVAILABLE

 Provides a comprehensive overview of the technologies involved in the manufacture and operation of liquid and gas targets for cyclotron based production of radioisotopes. The book covers the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, and target processing among others.
ENGLISH

Cyclotron Produced Radionuclides - Guidance On Facility Design And Production Of (18f)Fluorodeoxyglucose (Fdg)

by International Atomic Energy Agency

49,39€

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OUT OF STOCK OR NOT AVAILABLE

 Provides practical information for planning and operating a fluorodeoxyglucose (FDG) production facility, including design and implementation of the laboratories, facility layout, equipment, personnel and quality assessment of FDG.
ENGLISH

Radiopharmaceuticals For Sentinel Lymph Node Detection - Status And Trends

by International Atomic Energy Agency

36,00€

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OUT OF STOCK OR NOT AVAILABLE

 Summarizes the current status and future trends in the development of radiopharmaceuticals for sentinel lymph node detection (SLND), an essential diagnostic tool for the effective treatment of superficial cancers such as breast tumours and melanoma.
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Yttrium-90 And Rhenium-188 Radiopharmaceuticals For Radionuclide Therapy

ENGLISH

Yttrium-90 And Rhenium-188 Radiopharmaceuticals For Radionuclide Therapy

by International Atomic Energy Agency

47,33€

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OUT OF STOCK OR NOT AVAILABLE

 Presents recent studies aimed at investigating efficient quality control methods to ensure both the radionuclidic purity of generator eluates, and the proper preparation of new target specific 188Re and 90Y radiopharmaceuticals for various clinical applications.
ENGLISH

Production Of Long Lived Parent Radionuclides For Generators - 68ge, 82sr, 90sr And 188w

by Iaea

45,27€

free shipping

OUT OF STOCK OR NOT AVAILABLE

 Provides information on the production and processing of four important long lived parent radionuclides, 68Ge, 82Sr, 90Sr and 188W, used for the preparation of generators for nuclear medicine applications such as positron emission tomography and therapy.

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