Capa do artigo Current Topics In Microbiology And Immunology

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Current Topics In Microbiology And Immunology eBook

Name: Current Topics In Microbiology And Immunology
Price: 118.59 EUR
Author: H. Koprowski, E. Wecker, P. Koldovsky, W. Braun, W. Arber, R. Haas, W. Henle, P. H. Hofschneider, N. K. Jerne, O. Maaloe, R. Rott, H. G. Schweiger, M. Sela, L. Svru?Ek e P. K. Vogt
ISBN: 9783642654442

Ergebnisse Der Mikrobiologie Und Immunitätsforschung Volume 59

by H. Koprowski, E. Wecker, P. Koldovsky, W. Braun, W. Arber, R. Haas, W. Henle, P. H. Hofschneider, N. K. Jerne, O. Maaloe, R. Rott, H. G. Schweiger, M. Sela, L. Svru?Ek e P. K. Vogt

language: english

Publisher: Springer Berlin Heidelberg, December of 2012 ‧ see product details

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SYNOPSIS

Influenza continues to be one of the major epidemic diseases of man and is, in fact, his only remaining pandemic disease (BEVERIDGE, 1969). This is largely because influenza virus undergoes extreme antigenic variation, the mechanism of which is still poorly understood. Two kinds of antigenic variation occur in influenza viruses, antigenic drift and major antigenic shifts; both involve chan ges in the hemagglutinin and neuraminidase antigens on the surface of the virus. Antigenic drift, which involves gradual changes in the surface antigens of influenza virus, is thought to result from the selection by an immune popula tion of mutant virus particles with altered antigenic determinants. These mutants therefore possess a growth advantage in the presence of antibody (FRAN CIS and MAASSAB, 1965; ARCHETTI and HORSFALL, 1950; HAMRE et aI., 1958). It has been shown that antigenic mutants isolated in vitro by selection with antibody have changes in amino acid sequence in the polypeptides of the hem agglutinin subunits (LAVER and WEBSTER, 1968) and it is likely that antigenic drift in the neuraminidase occurs by the same mechanism.

DETAILS

Current Topics In Microbiology And Immunology

Ergebnisse Der Mikrobiologie Und Immunitätsforschung Volume 59

by H. Koprowski, E. Wecker, P. Koldovsky, W. Braun, W. Arber, R. Haas, W. Henle, P. H. Hofschneider, N. K. Jerne, O. Maaloe, R. Rott, H. G. Schweiger, M. Sela, L. Svru?Ek e P. K. Vogt
Property	Description
ISBN:	9783642654442
Publisher:	Springer Berlin Heidelberg
Release Date:	December of 2012
Language:	English
Format:	eBook
File Format and Compatibility:	PDF para ADE
Collection:	Current Topics In Microbiology And Immunology
Categories:	eBooks in English > Medicine > General Medicine
EAN:	9783642654442

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