Resultados de Pesquisa

INGLÊS

Physics Of Cancer, Volume 5 (Second Edition) - Magnetics- And Laser-Based Biophysical Techniques To Combat Cancer

de Claudia Tanja Mierke

~~152,70€~~ 137,43€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This is the fifth volume of the highly regarded Physics of Cancer (Second Edition) series, written with the aim of making very important topics in the physics of cancer visible to the research community. This fifth volume deals with biophysical methods. The first chapter presents the traditional NMR techniques and introduces the relatively new MRE technique for the characterization of cancer cells and tissues. The second chapter provides an overview of magnetic tweezer techniques relevant to cell characterization. The third chapter focusses on the magnetic twisting cytometry techniques. The fourth and fifth chapters discuss the cytoskeletal remodeling dynamics from a biological viewpoint and a physical viewpoint, respectively. The optical tweezer is introduced in the sixth chapter and the optical cell stretcher is discussed in the seventh chapter. In the eighth chapter, microfluidics-based high-throughput cell stretching is discussed and the latest developments are presented.Key Features<ul> <li>Fifth volume of the authors Physics of Cancer (Second Edition) books, a highly regarded series</li> <li>Comprises chapters that have been designed as self-contained units</li> <li>Written by a widely respected expert in the physics of cancer field</li> <li>Covers state-of-the-art techniques that were developed by the author</li> <li>Includes research findings that have been presented in numerous peer-reviewed journal articles</li> <li>Contains extensive references at the end of each chapter to enhance further study</li> </ul>
INGLÊS

Integrating Nanorobotics With Biophysics For Cancer Treatment

de Deepika Yadav, Gurvinder S Virk, Rishabha Malviya, Seifedine Kadry e Sonali Sundram

~~152,70€~~ 137,43€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 In this book, the authors explore the pros and cons of combining biophysics with micro and nanorobots for cancer treatment. This book offers the most recent findings on employing nano/microrobots in biophysics for cancer treatment. Insightful analysis and commentary from the authors complement a comprehensive survey of recent advances and ground-breaking research in the field. Chapters are followed by examples that illustrate the key points or applications of the material covered in that chapter, bridging the gap between the theoretical framework presented here and the rigorous investigation into the subject matter that awaits the reader, once they have mastered the material presented in the book.Key Features:<ul> <li>This book contains the most up-to-date information on using nano/microrobots in biophysics to treat cancer.</li> <li>Presents micro/nanorobot-based motile targeting medical devices for tumour treatment. Applications are discussed, along with the potential for their translation into clinical practice.</li> <li>This book illustrates the central ideas or practical applications of chapter topics, showing how the reader can move from the background knowledge presented in the volume to real-world research.</li> <li>Extensive references will be included at the end of each chapter to enhance further study.</li> </ul>
INGLÊS

Calcium Signals - From Single Molecules To Physiology

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Written by expert contributors, this much-needed book emphasizes a quantitative and comprehensive perspective to explore the many dimensions of cellular Ca2+ signalling. Leading researchers in the field of calcium signaling present key aspects of this process in cells, starting with Ca2+ entry into the cell, its uptake from the cytosol by organelles, such as the endoplasmic reticulum and mitochondria, and the actions of Ca2+ in turn on a variety of important cellular regulatory processes. This research and reference text should prove useful to a wide readership, from students to researchers at many different levels, particularly in physiology, pharmacology, or biomedical engineering.Key Features:<ul><li>Places a strong emphasis on Quantitative Biophysics</li></ul><ul><li>Acts as a unique resource for state-or-the-art methods to study Ca2+ signals</li></ul><ul><li>Includes emerging perspectives that link mechanistic insights to pathophysiological aspects of Ca2+ signalling</li></ul><ul><li>Discusses a historical perspective on the development of key ideas in the field</li></ul>
INGLÊS

Exocytosis: From Molecules To Cells

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book is divided into three sections: 1) Components of exocytotic pathways; 2) Biophysical insights from synthetic and reconstituted systems; and, 3) Physiological systems of exocytosis. The first section begins with a description of how secretory organelles form and are packaged with appropriate constituents for exocytosis. The second includes two chapters on recently published reconstituted systems of SNARE-mediated fusion. The final third of the book summarizes the cellular and molecular mechanisms of exocytosis and its regulation in diverse systems.This book is a reference for researchers and students in the fields of exocytosis and membrane trafficking who hope to gain a broad understanding of how these processes operate in various cell types. Historical perspectives on exocytosis are also presented and discussed.Key Features:<ul><li>Comprehensive and cohesive molecules-to-systems presentation of key features of secretory pathways.</li></ul><ul><li>Presents a single volume description of exocytosis regulatory mechanisms in many different cell types.</li></ul><ul><li>A number of chapter authors are highly regarded researchers in the field.</li></ul><ul><li>Detailed descriptions are provided of diverse systems of exocytosis including yeast exocytosis and exosomal secretion.</li></ul><ul><li>Incorporates methodologies that are routinely used by biophysicists to study exocytosis and membrane fusion including electrochemistry, electrophysiology, reconstitution assays, and high-resolution fluorescence imaging.</li></ul>
INGLÊS

Physics Of Cancer, Volume 4 (Second Edition) - Mechanical Characterization Of Cells

de Claudia Tanja Mierke

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This is the fourth volume of the highly regarded Physics of Cancer (Second Edition) series, written with the aim of making very important topics in the physics of cancer visible to the research community. This fourth volume deals with mechanobiology using biophysical methods. The first chapter deals with mechanosensing and mechanotransduction on vastly different length scales. The second chapter discusses biophysical techniques for mechanical phenotype characterization of cells and nuclei. The third provides an overview of the mechanical phenotype of the plasma membrane. The fourth chapter contains the latest insights into the mechanical assessment of cell spheroids, organoids and tumoroids. The basic approach of this text is to present the latest promising findings to the scientific community, addressing scientists at all career stages.Key Features<ul> <li>Fourth volume of the authors Physics of Cancer (Second Edition) books, a highly regarded series</li> <li>Comprises chapters that have been designed as self-contained units</li> <li>Written by a widely respected expert in the physics of cancer field</li> <li>Covers state-of-the-art techniques that were developed by the author</li> <li>Includes research findings that have been presented in numerous peer-reviewed journal articles</li> <li>Contains extensive references at the end of each chapter to enhance further study</li> </ul>
INGLÊS

Biopolymer Networks - Design, Dynamics And Discovery

de Rae M Robertson-Anderson

~~152,70€~~ 137,43€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This reference text provides a broad overview of biopolymer networks written for an interdisciplinary audience of cellular and molecular biologists, soft matter and polymer physicists, materials scientists, and chemical engineers. It opens with an introduction to biopolymers and their networks, followed by an overview of important polymer physics theories and concepts, experimental tools to measure network properties, and computational analysis techniques to characterize and interpret data. The book follows with a description of model biopolymer networks-from design to rheology-before embarking on a discussion of novel network designs and their emergent physical properties, including topologically-novel polymers, composites, active matter, and liquid-liquid phase separation. It closes with a community-led perspective on key open questions and grand challenges, and how we may come together to advance understanding of biopolymer networks and their utility in diverse applications.Key Features<ul> <li>Written to be highly interdisciplinary, suitable for relevant audiences in physics, biophysics, biology, chemistry, engineering, and materials science from the level of undergraduates to senior principal investigators.</li> <li>Highlights both foundational works as well as recent important findings, with a focus on recurring unifying themes and key open questions.</li> <li>Provides detailed descriptions of experimental methods for measuring mechanics, structure, and dynamics of biopolymer networks, including underlying principles, key components, important design and implementation considerations, advantages and disadvantages, and pro tips.</li> <li>Includes comprehensive discussion of computational analysis methods to characterize dynamics, rheology and structure of biopolymer networks, including underlying principles, algorithms, deliverables, limitations, and optimization considerations.</li> <li>Provides beginners guide to working with biopolymers and their networks and engineering networks to have specific properties</li> <li>Discusses networks of topologically-novel polymers as well as blends and composites of multiple distinct biopolymers.</li> <li>Provides comprehensive discussion of active, responsive and otherwise out-of-equilibrium biopolymer networks, including networks driven by molecular motors and enzymes as well as networks that undergo liquid-liquid phase separation.</li> <li>Features input from the community on the future of the field, grand challenges for applications in biology and materials science, and recommendations for collaborative endeavours to advance understanding of biopolymer networks and their applications.</li> </ul>
INGLÊS

Imaging In Particle Therapy - Current Practice And Future Trends

~~152,70€~~ 137,43€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 The benefits of Particle Therapy (PT), stemming from its physical and radiobiological advantages, necessitate the use of dedicated imaging technologies and approaches to ensure precise treatment planning and delivery. This book endeavors to establish a fundamental understanding of imaging within the context of PT, alongside exploring current research and clinical perspectives on its role. The focus is directed towards examining near-room, in-room, and in-beam technologies, both those already in clinical use and those in the developmental stage, which play pivotal roles in treatment planning, delivery, and verification processes, enabling adjustments either offline or online. Concurrently, the text addresses methodological solutions derived from these imaging modalities to effectively address challenges such as range uncertainties, anatomical variations, and biological properties, thereby enhancing the accuracy of treatment modeling and adaptation.Key Features<ul> <li>Presents a comprehensive overview of appropriate imaging modalities related to Particle Therapy (PT).</li> <li>Examines current and emerging near-room, in-room and in-beam technologies for treatment planning, delivery and verification, as well as adaptation.</li> <li>Describes methodological solutions, including mathematical modelling and AI strategies, to enable imaging for supporting anatomical and biological adaptation</li> <li>A number of chapter authors are expert researchers in the field.</li> </ul>
INGLÊS

Total Internal Reflection Fluorescence (Tirf) And Evanescence Microscopies - Total Internal Reflection Excitation And Near Field Emission

de Daniel Axelrod

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book offers a complete presentation of the physics, math, and experimental setups for both TIRF and related evanescence microscopies. It covers evanescence in both fluorescence excitation or emission. It also discusses, in detail, the theory, setups, and practical biological/biochemical applications for combinations of evanescence microscopies with other optical techniques such as polarization, photobleaching, correlation spectroscopy, scattering, image enhancement, optical force, two-photon, energy transfer, structured illumination, scanning, quenching, and single molecule detection. Physical and qualitative discussions augment the rigorous math, making the book accessible and interesting to a wide range of audiences with backgrounds from biology to chemistry to physics. The book also contains useful step-by-step guides to building, modifying, and aligning TIRF microscopy systems for specialized purposes.Key Features:<ul><li>Suitable for both basic and advanced levels</li></ul><ul><li>Offers combinations with related techniques</li></ul><ul><li>Relationship of evanescent effects between excitation and emission explained</li></ul><ul><li>Practical guide to the optics as well</li></ul>
INGLÊS

Physics Of Cancer, Volume 3 (Second Edition) - Experimental Biophysical Techniques In Cancer Research

de Claudia Tanja Mierke

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This is the third volume in the Physics of Cancer (Second Edition) set. The book introduces and discusses novel and advanced applications for probing and sensing mechanical properties of cells and their microenvironment. In addition, biophysical techniques for analysing combined biophysical techniques and cellular functions are presented and discussed. However, the major scope of the book is the presentation of biophysical approaches in cancer and its major findings that contribute significantly to the field of physics of cancer from a biophysical point of view. Each chapter is a closed unit and at its end references allow the reader to step more deeply into each topic. When possible, videos will be provided as a special feature to enhance the topics. Key Features<ul><li>Written by a highly respected researcher in emerging fields within mechanics and electrics based experimental techniques in biophysics. </li></ul><ul><li>Provides an authoritative coverage of cutting edge topics such as atomic force microscopy, cell-cell adhesion and traction force microscopy.</li></ul><ul><li>Third volume of the Second Edition of the highly respected Physics of Cancer series.</li></ul><ul><li>Features a sound introduction to cell and matrix mechanics and experimental techniques.</li></ul>
INGLÊS

Single-Particle Cryo-Em Of Biological Macromolecules

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. Furthermore, it is especially well suited for larger complexes and molecular machines, although it can also be used for macromolecules as small as 40 kDa or less. It also is especially well-suited to deliver high-resolution structural information about multiple conformational states.Key Features<ul><li>Written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM.</li></ul><ul><li>Provides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-article cryo-EM.</li></ul><ul><li>Covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results.</li></ul>
INGLÊS

Diabetes Systems Biology - Quantitative Methods For Understanding Beta-Cell Dynamics And Function

91,23€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Diabetes Systems Biology provides senior undergraduate students and junior scientists, interested in diabetes systems biology, with a tool to learn more about the mathematical models and methods used to understand macroscopically and microscopically beta-cell behaviour in health and disease. The book introduces readers to the quantitative methods used to examine beta-cell dynamics, islet biology and architecture, as well as diabetes etiology and implications. The goal is to allow junior researchers in the fields of mathematical biology and biophysics to obtain a broad understanding of these quantitative methods, and guide them into taking the first steps into the field of diabetes systems biology. At the end of each chapter, several problem-solving exercises (that require both analytical and computational skills) are provided for the readers to help them become more proficient in this field.Key Features<ul> <li> Comprehensive overview of all relevant aspects of diabetes systems biology and biological mathematical modelling</li> <li> Covers quantitative aspects of this discipline with embedded examples</li> <li> Features contributions from world-class researchers in the field</li> <li> Provides extensive references for further reading</li> <li> Includes problem solving exercises at the end of each chapter</li> </ul>
INGLÊS

Modeling And Simulating Cardiac Electrical Activity

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods.Key Features<ul> <li>Thorough introduction to the topic of mathematical modeling of electrical activity in the heart</li> <li>Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations</li> <li>In addition to being experts in the field, the contributing authors are expert science communicators</li> </ul>
INGLÊS

Solid-State Nmr - Applications In Biomembrane Structure

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book describes the methodology and applications of solid-state NMR spectroscopy to studies of membrane proteins, membrane-active peptides and model biological membranes. As well as structural studies it contains coverage of membrane interactions and molecular motions. Advances in biological solid-state NMR are very pertinent with high-field developments seeing applications in biological membranes and whole cells. Many of the chapter authors and contributors are world-class experts and leaders in the development and application of biological solid-state NMR. Key Features <ul> <li>Addresses principles, methods and applications of solid-state NMR methods to biomembrane studies</li> <li>Introduction to biological solid-state NMR and applications to biological membranes</li> <li>Structure and dynamics of membrane lipids, proteins and peptides</li> <li>NMR studies of membrane interactions and molecular motion</li> </ul>
INGLÊS

Biophysical And Chemical Properties Of Collagen: Biomedical Applications - Biomedical Applications

de Dr Veronica Glattauer e Professor John A.M. Ramshaw

152,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Collagen has proved to be a safe and effective biomedical material. Clinicians have used collagen-based devices in a wide range of applications with successful patient outcomes. This book gives an understanding of how present devices work, how they could be improved, and the development of new devices where a knowledge of collagen structure, chemistry and biology is required. The purification of collagen materials and the fabrication of a range of collagen products and their applications are covered within. Written by experts in the field, this text will be of interest for researchers as well as lecturers and students.
INGLÊS

Imaging In Particle Therapy - Current Practice And Future Trends

~~162,23€~~ 146,01€ 10% IMEDIATO

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INGLÊS

Spectroscopic Techniques For Cancer Diagnostics

~~162,23€~~ 146,01€ 10% IMEDIATO

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Physics Of Cancer, Volume 6 (Second Edition) - Cellular Mechanisms To Foster Or Fight Cancer

de Claudia Tanja (University Of Leipzig) Mierke

~~162,23€~~ 146,01€ 10% IMEDIATO

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INGLÊS

Physics Of Cancer, Volume 4 (Second Edition) - Mechanical Characterization Of Cells

de Claudia Tanja (University Of Leipzig) Mierke

162,23€ + 10% EM CARTÃO

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INGLÊS

Exocytosis: From Molecules To Cells

162,23€ + 10% EM CARTÃO

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INGLÊS

Single-Particle Cryo-Em Of Biological Macromolecules

162,23€ + 10% EM CARTÃO

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INGLÊS

An Introduction To Fluorescence Correlation Spectroscopy

de Radek (Nanyang Technological University) Machan, Sudipta (Tata Institute Of Fundamental Research (India)) Maiti e Thorsten (National University Of Singapore) Wohland

162,23€ + 10% EM CARTÃO

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INGLÊS

Principles Of Proteinâ€“Protein Association

de Professor Harold P (Duke University) Erickson

133,84€ + 10% EM CARTÃO

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INGLÊS

Physics Of Cancer: Second Edition, Volume 1 - Interplay Between Tumor Biology, Inflammation And Cell Mechanics

de Claudia Tanja (University Of Leipzig) Mierke

133,84€ + 10% EM CARTÃO

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INGLÊS

Integrating Nanorobotics With Biophysics For Cancer Treatment

de Deepika Yadav, Gurvinder S Virk, Rishabha (Galgotias University, Greater Noida, India) Malviya, Seifedine (Professor, Noroff University College (Norway)) Kadry e Sonali (Galgotias University, Greater Noida, India) Sundram

139,05€

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