Resultados de Pesquisa

INGLÊS

Receptor Tyrosine Kinases In Cancer

~~175,73€~~ 158,16€ 10% IMEDIATO

portes grátis

 font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman'; The emergence of small kinase inhibitors in cancer treatment offers a strategic approach to the management of cancer that surpasses the efficacy of traditional drugs.
INGLÊS

Role Of Autophagy And Reactive Oxygen Species In Cancer Treatment - Principles And Current Strategies

~~270,36€~~ 243,32€ 10% IMEDIATO

portes grátis

 While a combination of autophagy inhibitor and cytotoxic medicines is now being used in cancer treatment, investigating the potential of autophagy inhibitors for overcoming resistance to different anticancer medications and how this relates to the control of cancer micro environmental stressors raises several questions.
INGLÊS

Role Of Autophagy And Reactive Oxygen Species In Cancer Treatment - Principles And Current Strategies

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 While a combination of autophagy inhibitor and cytotoxic medicines is now being used in cancer treatment, investigating the potential of autophagy inhibitors for overcoming resistance to different anticancer medications and how this relates to the control of cancer micro environmental stressors raises several questions.
INGLÊS

Tumor Organoids

175,73€ + 10% EM CARTÃO

portes grátis

 Collectively, bioengineered tumors create an important resource for the in vitro study of tumor growth in 3D including tumor biomechanics and the effects of anti-cancer drugs on 3D tumor tissue.
INGLÊS

Tumor Dormancy And Recurrence

121,66€ + 10% EM CARTÃO

portes grátis

 This volume will be the first to provide a comprehensive description of tumor dormancy. The volume will serve as a fundamental instrument for every researcher and clinician interested in the field of tumor dormancy as well as a means of disseminating stimulating concepts and prompting the development of innovative technological solutions.
INGLÊS

Gene And Cellular Immunotherapy For Cancer

171,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These advances have dramatically improved the management of patients with relapsed refractory lymphoma, myeloma and leukemia. Gene and Cellular Immunotherapy for Cancer offers readers a comprehensive review of current cellular and gene-based immunotherapies. Divided into eighteen cohesive chapters, this book provides an in-depth and detailed look into cellular-based immunotherapies including CAR-T, TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers, focusing on their historical perspectives, biology, development and manufacturing, toxicities and more. Edited by two leading experts on gene and cellular immunotherapy, the book will feature chapters written by a diverse collection of recognized and up-and-coming experts and researchers in the field, providing oncologists, immunologists, researchers and clinical and basic science trainees with a bench to bedside view of the latest developments in the field.
INGLÊS

Molecular Targeted Radiosensitizers - Opportunities And Challenges

171,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.
INGLÊS

Unfolded Protein Response In Cancer

118,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This volume presents state-of-the-art information on each of the arms of the unfolded protein response (UPR), how their activation/repression are regulated, integrated, and coordinated, how UPR components affect cancer cell biology and responsiveness to therapeutic interventions, and how UPR components/activities offer potentially novel targets for drug discovery, repurposing, and development. The volume will provide the most recent information on the signaling and regulation of the UPR, explore examples of how the UPR and/or specific components contribute to cancer biology, and identify and explore specific examples of potently new actionable targets for drug discovery and development from within the UPR and its regulation. Unique to the volume will be a specific focus on the UPR and its role in cancer biology, as well as a discussion of the role of the UPR in drug responses and resistance in cancer.
INGLÊS

Innovations For Next-Generation Antibody-Drug Conjugates

175,73€ + 10% EM CARTÃO

portes grátis

 While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties.
INGLÊS

Estrogen Receptor And Breast Cancer - Celebrating The 60th Anniversary Of The Discovery Of Er

202,77€ + 10% EM CARTÃO

portes grátis

 The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer.
INGLÊS

Developments In T Cell Based Cancer Immunotherapies

175,73€ + 10% EM CARTÃO

portes grátis

 Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents.
INGLÊS

Targeting The Dna Damage Response For Anti-Cancer Therapy

243,33€ + 10% EM CARTÃO

portes grátis

 As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents thatmay have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR.
INGLÊS

Estrogen Receptor And Breast Cancer - Celebrating The 60th Anniversary Of The Discovery Of Er

198,09€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer.
INGLÊS

Cutaneous Melanoma

1013,90€ + 10% EM CARTÃO

portes grátis

 Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the definitive and most authoritative textbook on melanoma used worldwide.
INGLÊS

Attitudes Towards Europe Beyond Euroscepticism - Supporting The European Union Through The Crisis

de Danilo Di Mauro e Vincenzo Memoli

67,58€ + 10% EM CARTÃO

portes grátis

 The book addresses the topic of EU legitimacy by exploring the forms, origins and effects of citizens' support to EU institutions.
INGLÊS

East German Intellectuals And The Unification Of Germany - An Ethnographic View

de Dan Bednarz

121,66€ + 10% EM CARTÃO

portes grátis

 This book discusses the reunification of Germany and the negative impacts that this had on East German intellectuals. The book is an ethnographic account of how the intellectuals of East Germany reacted to the demise of their nation, their â€œdreamâ€ of a socialist world, and unification with capitalist West Germany.
INGLÊS

Innovations For Next-Generation Antibody-Drug Conjugates

171,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties.
INGLÊS

Targeting The Dna Damage Response For Anti-Cancer Therapy

237,84€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents thatmay have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR.
INGLÊS

Increasing The Therapeutic Ratio Of Radiotherapy

175,73€ + 10% EM CARTÃO

portes grátis

 Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues.
INGLÊS

Stat Inhibitors In Cancer

175,73€ + 10% EM CARTÃO

portes grátis

 This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context.
INGLÊS

Ex Vivo Engineering Of The Tumor Microenvironment

175,73€ + 10% EM CARTÃO

portes grátis

 This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo.
INGLÊS

Parp Inhibitors For Cancer Therapy

175,73€ + 10% EM CARTÃO

portes grátis

 PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer.
INGLÊS

Modern Marriage And The Lyric Sequence

de Jane Hedley

60,82€ + 10% EM CARTÃO

portes grátis

 Modern Marriage and the Lyric Sequence investigates the ways in which some of our best poets writing in English have used poetic sequences to capture the lived experience of marriage.
INGLÊS

Innovations For Next-Generation Antibody-Drug Conjugates

175,73€ + 10% EM CARTÃO

portes grátis

 While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties.
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