Resultados de Pesquisa

INGLÊS

Drug Delivery - Principles And Applications

169,53€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference.
INGLÊS

Drug Delivery - Principles And Applications

177,03€ + 10% EM CARTÃO

portes grátis

 Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference.
INGLÊS

Cyclic-Nucleotide Phosphodiesterases In The Central Nervous System - From Biology To Drug Discovery

145,68€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage.
INGLÊS

Dendrimer-Based Drug Delivery Systems - From Theory To Practice

218,56€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book focuses on the formulation and delivery of dendrimers. It offers both a comprehensive introduction and reference to practical applications. The coverage encompasses dendritic drug delivery systems ranging from dendrimers chemistry to cellular uptake of dendritic nanoparticles.
INGLÊS

Oral Bioavailability - Basic Principles, Advanced Concepts, And Applications

de Xiaoling Li

194,71€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Understanding bioavailability is critical to determining the amount of a drug to administer.
INGLÊS

Drug Design Of Zinc-Enzyme Inhibitors - Functional, Structural, And Disease Applications

286,53€ + 10% EM CARTÃO

portes grátis

 The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the pharmaceutical industry.
INGLÊS

Kinase Inhibitor Drugs

189,20€ + 10% EM CARTÃO

portes grátis

 Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the hottest drug targets in modern drug discovery.
INGLÊS

Plant Bioactives And Drug Discovery - Principles, Practice, And Perspectives

de Valdir Cechinel-Filho

222,53€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.
INGLÊS

Cyclic-Nucleotide Phosphodiesterases In The Central Nervous System - From Biology To Drug Discovery

151,35€ + 10% EM CARTÃO

portes grátis

 This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage.
INGLÊS

Hiv-1 Integrase - Mechanism And Inhibitor Design

197,36€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
INGLÊS

Medicinal Chemistry Of Nucleic Acids

194,71€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Covering all areas of the medicinal chemistry and therapeutic applications of nucleic acids, this book provides up-to-date coverage of the broad area of nucleic acid chemistry and biology.
INGLÊS

Carbohydrate Recognition - Biological Problems, Methods, And Applications

178,81€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
INGLÊS

Chemosensors - Principles, Strategies, And Applications

194,71€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Chemosensors?organic molecules designed to bind and sense small molecules or metal ions?function as molecular-level sensors that generate a signal upon binding.
INGLÊS

Oral Bioavailability - Basic Principles, Advanced Concepts, And Applications

de Xiaoling Li

201,36€ + 10% EM CARTÃO

portes grátis

 Understanding bioavailability is critical to determining the amount of a drug to administer.
INGLÊS

Evaluation Of Drug Candidates For Preclinical Development - Pharmacokinetics, Metabolism, Pharmaceutics, And Toxicology

147,01€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development. Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment this unique resource encourages integrated thinking in drug discovery. The contributors to this volume: Cover drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, stability, drug formulation, preclinical safety assessment, toxicology, and toxicokinetics Address developability issues that challenge pharma companies, moving beyond isolated experimental results Reveal connections between the key scientific areas that are critical for successful drug discovery and development Inspire forward-thinking strategies and decision-making processes in preclinical evaluation to maximize the potential of drug candidates to progress through development efficiently and meet the increasing demands of the marketplace Evaluation of Drug Candidates for Preclinical Development serves as an introductory reference for those new to the pharmaceutical industry and drug discovery in particular. It is especially well suited for scientists and management teams in small- to mid-sized pharmaceutical companies, as well as academic researchers and graduate students concerned with the practical aspects related to the evaluation of drug developability.
INGLÊS

Kinase Inhibitor Drugs

181,46€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the hottest drug targets in modern drug discovery.
INGLÊS

Aminoglycoside Antibiotics - From Chemical Biology To Drug Discovery

de Dev P. Arya

203,98€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Advances that open new avenues in developing aminoglycoside antibiotics During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new therapeutic targets for intervention.
INGLÊS

Carbohydrate-Based Vaccines And Immunotherapies

181,46€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Studies of vaccines derived from carbohydrate antigens have seen great progress. Synthetic carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids, have been explored or used to prevent and treat bacterial and viral infections, cancer, and other diseases.
INGLÊS

Drug-Drug Interactions In Pharmaceutical Development

de Binghe Wang

133,76€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage.
INGLÊS

Drug Design Of Zinc-Enzyme Inhibitors - Functional, Structural, And Disease Applications

280,83€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the pharmaceutical industry.
INGLÊS

Abc Transporters And Multidrug Resistance

185,43€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book gathers present knowledge on the involvement of ABC transporters in drug transport and resistance. Bringing together updated information from an otherwise-scattered field of scientific literature, this resource helps researchers in pharmaceutical science in discovering drugs able to counteract multidrug resistance in diseases like cancer.
INGLÊS

Computer Applications In Pharmaceutical Research And Development

226,51€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Computer Applications in Pharmaceutical Research and Development analyzes the use of computers through the entire pharmaceutical process of discovering, developing, and marketing new medicines.
INGLÊS

Glycogen Synthase Kinase 3 (Gsk-3) And Its Inhibitors - Drug Discovery And Development

203,98€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 GSK-3 is a promising drug target that has been extensively tested, and shown great potential for treatment of diseases that have no current effective treatment - like Alzheimer's, bipolar disorder, and cancer.
INGLÊS

Hiv-1 Integrase - Mechanism And Inhibitor Design

201,36€ + 10% EM CARTÃO

portes grátis

 This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery.
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