Resultados de Pesquisa

INGLÊS

Physiology And Pathophysiology Of Oligodendroglia

~~337,96€~~ 304,16€ 10% IMEDIATO

portes grátis

 This single volume provides a comprehensive description of oligodendroglia, the neural cells responsible for myelination of axons throughout the central nervous system.
INGLÊS

Neurophysiologic Biomarkers In Neuropsychiatric Disorders - Etiologic And Treatment Considerations

~~270,36€~~ 243,32€ 10% IMEDIATO

portes grátis

 This book reviews neurophysiological biomarkers in neuropsychiatric disorders from the viewpoint of the 21st Century Cures Act, which encourages the use of biomarkers for a variety of purposes during drug development.
INGLÊS

Astrocyte-Neuron Interactions In Health And Disease

~~270,36€~~ 243,32€ 10% IMEDIATO

portes grátis

 This new book extensively explores a range of topics related to astrocyte-neuron interactions under multiple conditions, in both health and disease.
INGLÊS

Engrams - A Window Into The Memory Trace

~~243,33€~~ 219,00€ 10% IMEDIATO

portes grátis

 This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date.
INGLÊS

Endogenous Opioids - From Basic Science To Biopsychosocial Applications

~~270,36€~~ 243,32€ 10% IMEDIATO

portes grátis

 This new volume provides a scientifically based exploration of the multifaceted world of endogenous opioids, including endorphins, enkephalins, dynorphins, endomorphins, and orphanin FQ/nociceptin, featuring a strong translational focus.
INGLÊS

Physiology And Pathophysiology Of Oligodendroglia

~~330,59€~~ 297,53€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This single volume provides a comprehensive description of oligodendroglia, the neural cells responsible for myelination of axons throughout the central nervous system.
INGLÊS

Neurophysiologic Biomarkers In Neuropsychiatric Disorders - Etiologic And Treatment Considerations

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This book reviews neurophysiological biomarkers in neuropsychiatric disorders from the viewpoint of the 21st Century Cures Act, which encourages the use of biomarkers for a variety of purposes during drug development.
INGLÊS

Systems Neuroscience

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 Among the topics covered in the new edition are artificial intelligence-assisted computational neuroscience for deciphering neural networks, spatial transcriptomics single cell sequencing, and exome/whole genome sequencing for understanding brain disorders in human genetics.
INGLÊS

Traumatic Brain Injuries - Navigating The Unique Terrain Of The Injured Young And Aged Brains

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 <p>This book focuses on the clinical and preclinical research on traumatic brain injuries where age at time of injury (young versus aged) reveals both parallel and divergent findings at the molecular, cellular, and behavioral levels with insights into alterations in brain structure and function and the implications for recovery. The authors address the hurdles that have been overcome, consider new directions inspired by the most recent research, and the value of data sharing and evidenced based-practice. <em><em>Traumatic Brain Injuries: Tackling the Unique Terrain of the Injured Young and Aged Brain </em></em>explores the challenges imposed by an injury that not only causes tissue damage but disrupts brain development and may incite pathological events in the aging brain. With the proliferation of the research literature in traumatic brain injuries, this is the time for a book that surveys the landscape and assesses where the field is headed and what is needed moving forward. </p>
INGLÊS

Microglia - Physiology, Pathophysiology And Therapeutic Potential

~~370,34€~~ 333,31€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 The past decade has witnessed a revolution in our understanding of microglia, especially since their roles in the healthy CNS have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their crucial involvement with diseases. Edited by Drs. Marie-Ève Tremblay and Alexei Verkhratsky, <i>Microglia:</i> <i>Physiology, Pathophysiology and Therapeutic Potential</i> shares with the scientific and medical community the latest discoveries in the microglial research field, with a truly comprehensive collection of chapters written by the top specialists across five continents. The book begins by explaining briefly what they are, from both historical and evolutionary points of view, and how they can be studied. The first section explains their physiological roles in the maturation, function, and plasticity of the CNS. The second section focuses on their general involvement in neuropathophysiology, and the third section on their critical implication in specific CNS diseases, including neurotrauma, neuropathic pain, ischemia and stroke, infectious diseases, autoimmune diseases, neurodevelopmental and neuropsychiatric disorders, substance use and addiction, sleep disorders, ageing, and neurodegenerative diseases. The fourth section presents their clinical potential as a targeted therapeutic tool for these CNS diseases.<div><p></p></div>
INGLÊS

Astrocyte-Neuron Interactions In Health And Disease

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This new book extensively explores a range of topics related to astrocyte-neuron interactions under multiple conditions, in both health and disease.
INGLÊS

Engrams - A Window Into The Memory Trace

~~237,84€~~ 214,06€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date.
INGLÊS

Endogenous Opioids - From Basic Science To Biopsychosocial Applications

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This new volume provides a scientifically based exploration of the multifaceted world of endogenous opioids, including endorphins, enkephalins, dynorphins, endomorphins, and orphanin FQ/nociceptin, featuring a strong translational focus.
INGLÊS

Drug Development In Psychiatry

~~270,36€~~ 243,32€ 10% IMEDIATO

portes grátis

 Novel drugs and disease targets have changed the way developers and regulatory agencies think about clinical trial methodology.The book elucidates how biomarkers, genetics and advances in neuroscience and neuroimaging have influenced drug development approaches, which will ultimately change the practice of psychiatry.
INGLÊS

Dendritic Spines - Structure, Function, And Plasticity

243,33€ + 10% EM CARTÃO

portes grátis

 This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system.
INGLÊS

Fractal Geometry Of The Brain

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 <div>The new edition of the highly popular, <i>The Fractal Geometry of the Brain</i>, reviews the most intriguing applications of fractal analysis in neuroscience with a focus on current and future potential, limits, advantages, and disadvantages. It brings an understanding of fractals to clinicians and researchers even if they do not have a mathematical background, and it serves as a valuable tool for teaching the translational applications of computational fractal-based models to both students and scholars. As a consequence of the novel research developed at Professor Di Ieva''s laboratory and other centers around the world, the second edition will explore the use of computational fractal-based analysis in many clinical disciplines and different fields of research, including neurology and neurosurgery, neuroanatomy and psychology, magnetoencephalography (MEG), eye-tracking devices (for the fractal computational characterization of "scanpaths"),deep learning in image analysis, radiomics for the characterization of brain MRIs, characterization of neuropsychological and psychiatric diseases and traits, signal complexity analysis in time series, and functional MRI, amongst others.<br></div>
INGLÊS

Dendritic Spines - Structure, Function, And Plasticity

237,84€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system.
INGLÊS

Molecular Mechanisms Of Neurotransmitter Release

238,49€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <div><div>Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated calcium channels and ryanodine receptors), and the regulation of neurotransmitter release by potassium channels, cell adhesion molecules, lipids, aryl hydrocarbon receptor-interacting protein (AIP), presenilins, and calstabins. To aid in understanding and illustrate key concepts, the book includes sufficient background information and a wealth of illustrations and diagrams. The new edition includes major updates to previous chapters, as well as several new chapters that reflect the recent advances in the field. Comprehensive and cutting-edge, <i>Molecular Mechanisms of Neurotransmitter Release</i>, <i>2nd edition</i>, is a valuable learning resource for neuroscience students and a solid reference for neuroscientists.<br></div><div><br></div><div><br></div></div>
INGLÊS

Progress In Nanomedicine In Neurologic Diseases

237,84€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <div>This book covers the use of nanomedicine in the delivery of neuroprotective agents, including pharmacological drugs, stem cells, neurotrophic factors, monoclonal antibodies<b> </b>and enzymes to induce greater beneficial effects in neurologic diseases. Thus, the main purpose of the book is to explore the delivery of drugs either alone or in combination with stem cells to enhance neuroprotection in neurological diseases. Brain pathology associated with acute trauma such as head injury and brain blast injury can also be managed using novel treatment strategies. In addition, emphasis is made that standard patterns of brain pathology may be complicated with multiple comorbidity factors where one agent alone is not sufficient to induce brain protection. Enzymes and antibodies may help in combination and enhance the efficacy when administered through nanotechnology. Progress in <i>Nanomedicine in Neurologic Diseases</i> will encourage further research in the field of neuroprotection, brain injury, neurodegenerative diseases, neuropharmacology, neuropathology, and neurology. Students and researchers along with policy makers, teachers and health care professionals may also benefit from the findings of the book for enhanced patients care.<br></div>
INGLÊS

Basic And Translational Applications Of The Network Theory For Dystonia

198,74€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <p>A recently proposed novel scheme of dystonia suggests that it is a disorder of neural network. Impairment in any of the "nodes" of the network may result in deficient network activity, causing dystonia. This book aims to present various experimental evidence supporting the network theory of dystonia. Dystonia is the abnormal twisting and turning of the organ and associated involuntary oscillations. Although dystonia is less common than Parkinson’s disease, traumatic brain injury, or stroke, each of these common disorders present with dystonia. Information regarding the brain regions that may be involved in dystonia is surprisingly limited and often conflicting. With chapters written by subject matter experts, this is a unique title that focuses on dystonia as a network disorder. This book would be of interest to basic and clinical researchers with an interest in motor systems and movement disorders.</p><br>
INGLÊS

Vertebrate Motoneurons

243,33€ + 10% EM CARTÃO

portes grátis

 This book aims to provide a comprehensive and timely review of new findings in motoneuron research. These novel findings are revolutionizing ideas about the function of motoneurons and have important implications for motoneuron disease.
INGLÊS

Drug Development In Psychiatry

270,36€ + 10% EM CARTÃO

portes grátis

 Novel drugs and disease targets have changed the way developers and regulatory agencies think about clinical trial methodology.The book elucidates how biomarkers, genetics and advances in neuroscience and neuroimaging have influenced drug development approaches, which will ultimately change the practice of psychiatry.
INGLÊS

Holocaust Fiction And The Question Of Impiety

de David John Dickson

135,18€ + 10% EM CARTÃO

portes grátis

 This book discusses the issues underlying contemporary Holocaust fiction. Using Gillian Roseâ€™s theory of Holocaust piety, it argues that, rather than enhancing our understanding of the Holocaust, contemporary fiction has instead become overly focused on gratuitous representations of bodies in pain.
INGLÊS

Patterns Of Parental Behavior - From Animal Science To Comparative Ethology And Neuroscience

121,66€ + 10% EM CARTÃO

portes grátis

 It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild.
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