Resultados de Pesquisa

INGLÊS

Reproductive Endocrinology And Biology

100,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 We have now reached the mid-point of our editorial task of putting together the compendium, Principles of Medical Biology, which is supposed to be composed of twenty-five modules. The present single-volume module on reproductive endocrinology and biology is in more than one respect a continuation of Module 10 (in two volumes) dealing with molecular and cellular endocrinology. In addition, it intersects, as it should, with various parts of obstetrics and gynaecology, both of which are abetted by technology. One has only to recall that the practical benefits of ultrasound in perinatal medicine and in vitro fertilisation are the outcome of the technological revolution in biomedicine. Whether we are approaching a new era in reproductive biology following the invention of animal cloning is still hard to tell. For some people, it remains an article of faith that cloning of the human being is highly probable. For others, asexual reproduction is anathema. It should surely be obvious to us all that somatic cell nuclear transfer technology (SCNTT) is going to be at its strongest in dealing with husbandry. Whether this and several social forces will alter our modern outlook, there can be little doubt.As in diverse clinical and basic research, so in obstetrics, animals are used as a model. The data thus obtained is extrapolated, if valid, to the mother and foetus. The success of this approach is exemplified in studies carried out on sheep as a model. On the whole, it is also quite apparent that progress in the field of reproductive biology is to a large extent ascribable to the discovery in other disciplines of new hormones, as well as the introduction of new tools and recent improvements in laboratory methods including measurement of hormones.
INGLÊS

Cell Chemistry And Physiology: Part Iii

99,38€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Consisting of chapters on the nature of membrane transport systems, this work includes co-transport systems namely, Na+ -K+ -2CI-, KCI, -HCO-3, as well as CI- -HCO-3 exchange and K+ and CI- movements through channels. It also reveals that calometric measurements are useful in studies of clinical and toxicological problems.
INGLÊS

Membranes And Cell Signaling

96,73€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 It should not come as too much of a surprise that biological membranes are considerably more complex than lipid bilayers. This has been made clear by the fluid-mosaic model which considers the cell membrane as a two-dimensional solution of a mosaic of integral membrane proteins and glycoproteins firmly embedded in a fluid lipid bilayer matrix.
INGLÊS

Microbiology

125,88€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 There is a need in small group teaching for a readable module that provides a balanced treatment of the four main areas of medical microbiology-bacteriology, mycology, virology and parasistology. It need not be encyclopedic in scope nor didactic, but it should emphasise principles and concepts. Any existing gaps in this type of presentation are, of course, left for the student to fill.Some subject material has been excluded. An example is a chapter on laboratory procedures including PCR for rapid bacterial and viral diagnosis. The discussion of bacterial sexually transmitted diseases does not cover goncoccal infections. This is not a serious matter because the tutor can assign the topic to the students. Moreover, we have reluctantly omitted a separate chapter on anaerobic bacteria. The subject of nosocomial pathogens is touched upon but not in sufficient detail (e.g., control). These bacteria (e.g., S. aureus, E. coli and pseudomonas) are found in hospitals and are resistant to disinfectants and antibiotics. A new but serious problem is the emergence of resistance to antiviral agents.Without question, molecular biology owes more to the study of viruses than bacteria. The fact remains, however, that effective therapy against most viral diseases is not yet available. Perhaps one of the most dramatic examples of this situation is the fight against the AIDS virus and the search for a vaccine. The public health challenge of AIDS remains formidable in spite of the recent encouraging results obtained with protease inhibitor therapy. At the moment at least six receptors for HIV are known to be present in human cells. One of them is the CCR5 receptor in the absence of which cells fail to get infected with the virus. Drugs that can interrupt CCR5 binding sites on the virus envelope are being vigorously sought. Thus, Volume 9B gives a large place to HIV disease.The last group of chapters highlight several features of microbiology which are also of clinical importance and heuristic value. The chapter on fever of unknown origin provides fertile soil for problem based learning.
INGLÊS

Cell Chemistry And Physiology: Part Iv

99,38€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Tells how the traditional boundaries of cell chemistry and physiology are being erased by molecular biology. This book deals with the chemistry of actin and myosin and contains chapters on cell motility, ATP synthesis in muscle, and contraction in smooth and skeletal muscle.
INGLÊS

Molecular And Cellular Genetics

92,68€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The tools of molecular biology have revolutionised our understanding of gene structure and function and changed the teaching of genetics in a fundamental way. The transition from classical genetics to molecular genetics was initiated by two discoveries. One was the discovery that DNA has a complementary double helix structure and the other that a universal genetic code does exist. Both led to the acceptance of the central dogma that RNA molecules are made on DNA templates. The last twenty years have seen remarkable growth in our knowledge of molecular genetics, most of which is the outcome of recombinant DNA technology. This technology which is not limited to cloning, sequencing, and expression has created a biotechnology industry of its own, the purpose of which is to develop new diagnostic and therapeutic approaches in medicine. Both industries in collaboration with the biomedical community are now engaged in laying down the foundation of molecular medicine. The present volume seeks to provide a coherent account of the new science of molecular genetics. Its content however is by no means exhaustive, partly because of the publication explosion but more because of space restrictions. A rudimentary knowledge of genetics on the reader's part is assumed. Quite understandably, considerable emphasis is placed on major technical advances but not without expounding numerous new ideas and phenomena including alternative splicing, POR, DNA methylation, genomic imprinting, and so on.
INGLÊS

Cellular Organelles

58,29€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The purpose of this volume is to provide a synopsis of present knowledge of the structure, organisation, and function of cellular organelles with an emphasis on the examination of important but unsolved problems, and the directions in which molecular and cell biology are moving. Though designed primarily to meet the needs of the first-year medical student, particularly in schools where the traditional curriculum has been partly or wholly replaced by a multi-disciplinary core curriculum, the mass of information made available here should prove useful to students of biochemistry, physiology, biology, bioengineering, dentistry, and nursing.It is not yet possible to give a complete account of the relations between the organelles of two compartments and of the mechanisms by which some degree of order is maintained in the cell as a whole. However, a new breed of scientists, known as molecular cell biologists, have already contributed in some measure to our understanding of several biological phenomena notably interorganelle communication. Take, for example, intracellular membrane transport: it can now be expressed in terms of the sorting, targeting, and transport of protein from the endoplasmic reticulum to another compartment. This volume contains the first ten chapters on the subject of organelles. The remaining four are in Volume 3, to which sections on organelle disorders and the extracellular matrix have been added.
INGLÊS

Cell Chemistry And Physiology: Part I

58,29€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 An introduction to the study of cell chemistry and physiology. This volume is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are useful to an understanding of cell biology, and those that are important in the teaching of modern medicine.
INGLÊS

Development Biology

100,70€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The purpose of this module is to provide a survey of the rapidly expanding field of developmental biology and to introduce it to the student in a unifying way. In medical schools where courses in biochemistry, physiology, and pharmacology are already considerably intersecting, there is not surprisingly a rising demand in modern medical education for books emphasizing the interdisciplinary approach. In recent years, developmental biology has become a very vibrant and exciting field. The adoption of the interdisciplinary approach in this field has yielded enormous information about how DNA is able to produce a living organism from a fertilized egg. The discovery of 'master' genes in Drosophila that control spatial organization and share a segment of DNA, the so-called homeobox, and the discovery in C. elegans of genes controlling the timing of branching off of cell lineages are today recognized as milestones in molecular developmental biology.Because of space limitations and because of the information explosion, we have continued to pursue the policy of selecting broad topics but not in every case. This time, for example, though guided by the principle that a close connection exists between genes, adhesion, and morphogenesis, we opted to include certain topics such as cadherin - an adhesion molecule - rather than have the whole subject of adhesion dealth with in a single chapter. Substrate-adhering molecules (e.g., fibronectnin) are touched upon in Chapter 5. In a similar manner, only one type of junction is discussed at length. Chapters 8, 9, and 10 border on the extraordinary, for they are together absorbingly interesting. The last chapter makes things more pragmatic. The attention of the reader is drawn to the fact that several previous volumes of the compendium impinge on the present one. Chapters 25 and 26 in Volume 7B, in particular, have much to say on the subjects of extracellular matrix adhesion and intercellular communication.
INGLÊS

Immunobiology

92,68€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 As this volume demonstrates, immunobiology is a young science which is undergoing explosive growth. Judged by results, it is already an elaborate discipline which cuts across every other area in biomedical research and even has its own vocabolary (e.g., the "veto" effect). Rather than inculcate the habit of superficial learning by having the student go through a maze of details, we have sought to gather together sixteen essays that range from T-cells to psyhoneuroimmunology. This is keeping with the growing understanding that the student is expected to read and think far more for herself/himself.Next to nothing is known about innate immunity. However, recent evidence suggests that collectins might bridge the gap between innate immunity and specific clonal immune responses. Collectins are soluble effector proteins that include serum mannose-binding protein, and lung surfactants A and D. They are considered to be ante-antibodies.
INGLÊS

Cell Chemistry And Physiology: Part Ii

99,38€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This volume illustrates the extent to which the traditional distinction between biochemical and physiological processes is being obliterated by molecular biology. It can hardly be doubted that the revolution in cell and molecular biology is leading to core knowledge that provides an outline of the integrative and reductionist approach. We view this as the beginning of a new era, that of the integration of learning.As in the preceding volumes, the choice of topics has been deliberate not only because of the need to keep the volume within reasonable bounds but also because of the need to avoid information over-load. Several relevant topics are dealt with in other modules; for example, the role of G proteins in transmembrane signalling is covered in the Membranes and Cell Signalling module (i.e., Volume 7). Omissions are of course inevitable but they are minor. A case in point is the subject of phosphatases, the treatment of which does not take into account calcineurin. One of the key functions of this Ca2+ -activated protein phosphatase that is also regulated by calmodulin is to desphosphorylate voltage-dependent Ca2+ channels. The mere recognition of such omissions before or after consulting textbooks and journals should be a spur to a more complete discussion by the student of the subject in a small group teaching setting.
INGLÊS

Biological Psychiatry

132,50€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Dramatic advances in biological psychiatry have attested to the staying power of the experimental method. Those who made this revolution in knowledge happen are a breed of investigators availing themselves of the tools of molecular biology, pharmacology, genetics, and perhaps, above all, the technology of neuroimaging.
INGLÊS

Liver In Biology And Disease - Liver Biology In Disease, Hepato - Biology In Disease

111,30€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. With this intention in mind, a volume of this nature takes into account the close dependence of progress in the medical sciences on bioinformatics (gene and protein analysis) or more precisely, computational biology and of course, the Internet. In general, it follows the pattern of its predecessors.*Chapters are illustrated with numerous figures and references are current*Clear, concise and accurate text about a large number of liver diseases*Describes the liver's histology, biochemistry, and pathology in molecular terms
INGLÊS

A Flower In A Box

de Bradley Perera

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INGLÊS

Islam: The Armageddon Bomb - The Armageddon Bomb

de Rev. Stephen Jumaat Abdul-Razaq

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INGLÊS

Islam: The Armageddon Bomb - The Armageddon Bomb

de Rev. Stephen Jumaat Abdul-Razaq

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INGLÊS

Just A Glance

de Seamus Omeara

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INGLÊS

Freewill - The Degree Of Freedom Within

de Jesse Omoregie

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INGLÊS

Challenges Of Christian Marriage In African Culture

de Sylvester Oyeka

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INGLÊS

Challenges Of Christian Marriage In African Culture

de Sylvester Oyeka

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INGLÊS

The Lantern

de Tanya Tiedje

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A Mind Full Of Poems: In This Present Moment - In This Present Moment

de Nicholas Bingham

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INGLÊS

A Mind Full Of Poems: In This Present Moment - In This Present Moment

de Nicholas Bingham

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INGLÊS

The Hand Of God: Taken - Taken

de Malcolm Ward

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