Resultados de Pesquisa

INGLÊS

Advances In Adrenergic Receptor Biology

160,33€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Focuses on Adrenergic Receptor Biology. This title includes discussions of the role and relationship of adrenergic receptors to different systems and diseases.
INGLÊS

Structure And Function Of Calcium Release Channels

160,33€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization. This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers.
INGLÊS

Chloride Channels

58,29€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The amount of new information on the molecular biology of chloride channels has grown tremendously in recent years. This large amount of information gives some unique and, in some instances, surprising insights into the function and structure of chloride channels which are present in every cell. This volume contains a series of in-depth reviews of chloride channel physiology, biophysics, and molecular biology. The reviews cover chloride channels found in the plasma membrane as well as in organelles of both plant and animal cells.Key Features* Discusses CFTR, the cystic fibrosis transmembrane regulator, which is responsible for CF and the CIC-family of chloride channels responsible for myotonia congenita* In-depth reviews of chloride channel physiology, biophysics, and molecular biology* Reviews chloride channels found in the plasma membrane and in organelles of both plant and animal cells
INGLÊS

Cell Biology And Membrane Transport Processes

58,29€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This volume brings together contributors from several different fields of cell biology, physiology, and molecular biology. The common thread that runs through all of the work presented is that cell processes regulate the activities of membrane transport proteins and classes of membrane transport proteins participate in a number of critical cell phenomena. This volume is unique in covering three different members of the ATP Binding Cassette family (MDR, CFTR and STE6) in one place, as well as in including structure and function analysis of the sodium pump in the same forum where its cell biology is considered. The book will appeal to a broad range of biologists with interests in membrane transport, membrane biology, cell biology, and sorting.
INGLÊS

Eye'S Aqueous Humor

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 A study of cellular membranes. It discusses transport; ocular aquaporins and aqueous humor dynamics; the role of Gap junction channels in the ciliary body secretory epithelium; regional dependence of inflow; functional modulators linking inflow with outflow of aqueous humor; aqueous humor outflow resistance; and aqueous humor dynamis.
INGLÊS

Computational Modeling Of Membrane Bilayers

de V. Sundararajan

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. - Discusses the current state of electrostatics in biomolecular simulations and future directions- Includes information on time and length scales in lipid bilayer simulations- Includes a chapter on the nature of lipid rafts
INGLÊS

Free Radical Effects On Membranes

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Offers an approach to topics relevant to the study of cellular membranes. This work provides an overview on biomembranes and the impact their physico-chemical properties have on reactive species reactivity. It focuses on reactive species and control of cell-signaling pathways.
INGLÊS

Lipid Polymorphism And Membrane Properties

165,63€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The major lipid components of biological membranes can undergo many diverse morphological rearrangements. Studies of these diverse phases and the manner in which they are formed tends to alter the properties of ordinary bilayer membranes. This book examines the structural and biological roles of lipids forming non-lamellar structures.
INGLÊS

Membrane Protein-Cytoskeleton Interactions

160,33€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
INGLÊS

Potassium Ion Channels: Molecular Structure, Function, And Diseases

165,63€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Many diseases are caused by the abnormalities of potassium ion channels. They include diabetes mellitus, life-threatening hereditary cardiac arrhythmia, epilepsy, neural degeneration, and renal hypertension. This book focusses on potassium ion channels and covers the progress made in research on these proteins.
INGLÊS

Gap Junctions: Molecular Basis Of Cell Communication In Health And Disease

165,63€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 In both vertebrates and invertebrates, cell coupling is mediated by channels clustered at cell-to-cell contact domains known as gap junctions. This text focuses on the molecular basis of channel function in health and disease. Twenty-eight contributions from Peracchia (pharmacology and physiology,
INGLÊS

Cell Lipids

58,29€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Topics on cell lipids vary from basic themes such as biosynthesis and membrane distribution to the role of lipids in intracellular signalling and membrane flow. This single volume also highlights the roles of lipids in eukaryotic cells and discusses organization of lipids in microdomains.
INGLÊS

Membrane Permeability: 100 Years Since Ernest Overton

165,63€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. - Provides an historical perspective of Overton's contributions to the theory of narcosis- Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion
INGLÊS

Amiloride-Sensitive Sodium Channels: Physiology And Functional Diversity

165,63€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations. - Summarizes current state of amiloride-sensitive sodium channel field- Analyzes structure-function of epithelial sodium channels- Discusses immunolocalization of epithelial sodium channels- Examines hormonal regulation of sodium channels- Discusses sodium channels in lymphocytes, kidney, and lung- Considers mechanosensitivity of sodium channels- Provides ideas on sodium channels and disease
INGLÊS

Eye'S Aqueous Humor: From Secretion To Glaucoma

165,63€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This volume presents a basic consensus of how the aqueous humour is formed and exits through the trabecular meshwork and canal of Schlemm. It presents an update to current knowledge on the molecular transport mechanisms which underlie aqueous humour dynamics.
INGLÊS

Extracellular Nucleotides And Nucleosides: Release, Receptors, And Physiological & Pathophysiological Effects

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Purinergic receptors are proteins that bind ATP as their extracellular ligand. Once thought only as an intracellular molecule that provides energy, ATP is also now considered an essential autocrine/paracrine agonist that acts extracellularly within tissues and tissue microenvironments. Receptors for ATP and its metabolites, so-called "purinergic receptors," are essential membrane receptors that transduce the extracellular signal carried by ATP. Many cell types or tissues express multiple types of these receptors, often on the same cell. This volume will cover the history and overall impact of extracellular ATP signaling, methods to detect ATP release and signaling, the molecular and cell biology of purinergic receptors, the pharmacology of purinergic receptors, the ion channel biophysics and biochemistry of P2X purinergic receptor channels, and the physiology and pathophysiology of purinergic receptors.Key Features* Organized and written by world-renowned experts* Covers state-of-the-art experimental methods* Has broad appeal to basic and clinical scientists, the biotch industry and pharmaceutical research companies
INGLÊS

Mechanosensitive Ion Channels, Part A

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include The Mechanical Properties of Bilayers; Molecular Dynamic Modeling of MS Channels; Structures of the Prokaryotic Mechanosensitive; Channels MscL and MscS; 3.5 Billion Years of Mechanosensory Transduction: Structure and Function of Mechanosensitive Channels in Prokaryotes; Activation of Mechanosensitive Ion Channels by Forces Transmitted through Integrins and the Cytoskeleton; Thermodynamics of Mechanosensitivity; Flexoelectricity and Mechanotransduction; Lipid Effects on Mechanosensitive Channels; Functional Interactions of the Extracellular Matrix with Mechanosensitive Channels; MSCL: The Bacterial Mechanosensitive Channel of Large Conductance; The Bacterial Mechanosensitive Channel MscS: Emerging Principles of Gating and Modulation; Structure function relations of MscS; The MscS Cytoplasmic Domain and its Conformational Changes upon the Channel Gating; Microbial TRP Channels and Their Mechanosensitivity; MSCS-Like Proteins in Plants; Delivering Force and Amplifying Signals in Plant Mechanosensing; MS Channels in Tip Growing Systems.
INGLÊS

Aquaporins

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Aquaporins summarizes the present knowledge in this expanding field of research, starting with the structural analysis of water channel proteins. Subsequent chapters begin with mammalian aquaporins, examining physiology and pathophysiology, analysis of knock-out model animals, and the regulation of aquaporin function. Also covered is the distribution and regulation of aquaporins in plants and the function of water and glycerol channels in microbial systems. - Comprehensive treatment of a topical research field- Authored by world leaders in the field- Covers structural biology and physiology- Covers different experimental and biological systems- Chapters on plant and microbial systems- Extensive treatment of mammalian physiology and pathophysiology- Structural analysis excellently illustrated
INGLÊS

Peptide-Lipid Interactions

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion.Key Features* world-renowned experts* state-of-the-art experimental methods* monolayers, bilayers, biological membranes * theoretical aspects and computer simulations* rafts* synaptic transmission* membrane fusion* signal transduction
INGLÊS

Nociceptive Membrane

172,25€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Membranes are essential cellular organelles. They not only define cells and other organelles, but also are critical in the cell function by selectively regulating the passage of molecules by acting as a matrix for other signaling molecules. This title covers Nociceptive Membrane. It is intended for practicing scientists and students.
INGLÊS

Extracellular Vesicles: Advances And Perspectives In Treatments, Therapies, And Vaccination

~~191,97€~~ 172,77€ 10% IMEDIATO

portes grátis
INGLÊS

Ion Channels In Cellular Pathophysiology Part A

~~191,97€~~ 172,77€ 10% IMEDIATO

portes grátis
INGLÊS

Parasitic Protozoa Membranes - Structure, Singularities And Host-Pathogen Interaction

ESGOTADO OU NÃO DISPONÍVEL
INGLÊS

Extracellular Vesicles From Basic Research To Clinical Applications

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