Resultados de Pesquisa

INGLÊS

Bioinformatics - An Introduction

de Jeremy Ramsden

79,49€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <p>This invaluable textbook presents a self-contained introduction to the field of bioinformatics. Providing a comprehensive breadth of coverage while remaining accessibly concise, the text promotes a deep understanding of the field, supported by basic mathematical concepts, an emphasis on biological knowledge, and a holistic approach that highlights the connections unifying bioinformatics with other areas of science.</p><p>The thoroughly revised and enhanced fourth edition features new chapters focusing on regulation and control networks, the origins of life, evolution, statistics and causation, viruses, the microbiome, single cell analysis, drug discovery and forensic applications. This edition additionally includes new and updated material on the ontology of bioinformatics, data mining, ecosystems, and phenomics. Also covered are new developments in sequencing technologies, gene editing methods, and modelling of the brain, as well as state-of-the-art medical applications. Of specialtopicality is a new chapter on bioinformatics aspects of the coronavirus pandemic.</p><p><b>Topics and features:</b></p><ul><li>Explains the fundamentals of set theory, combinatorics, probability, likelihood, causality, clustering, pattern recognition, randomness, complexity, systems, and networks</li><li>Discusses topics on ontogeny, phylogeny, genome structure, and regulation, as well as aspects of molecular biology</li><li>Critically examines the most significant practical applications, offering detailed descriptions of both the experimental process and the analysis of the data</li><li>Provides a varied selection of problems throughout the book, to stimulate further thinking</li><li>Encourages further reading through the inclusion of an extensive bibliography</li></ul><p>This classic textbook builds upon the successful formula of previous editions with coverage of the latest advances in this exciting and fast-moving field. With its interdisciplinary scope, this unique guide will prove to be an essential study companion to a broad audience of undergraduate and beginning graduate students, spanning computer scientists focusing on bioinformatics, students of the physical sciences seeking a helpful primer on biology, and biologists desiring to better understand the theory underlying important applications of information science in biology.</p><p></p><p><b>Dr. Jeremy Ramsden</b> is Hon. Prof. of Nanotechnology in the Department of Biomedical Research at the University of Buckingham, UK.</p><p></p><p></p><p></p><p></p>
INGLÊS

Innovative Product Development By Additive Manufacturing 2021

189,25€ + 10% EM CARTÃO

portes grátis

 The yearly conference used to be held in German under the title: â€œKonstruktion fÃ¼r die Additive Fertigung.â€ The topics are: â€¢ Design and optimization â€¢ Simulation, validation and quality assurance â€¢ Specifications, potentials and solutions
INGLÊS

High-Performance Algorithms For Mass Spectrometry-Based Omics

de Fahad Saeed e Muhammad Haseeb

121,66€ + 10% EM CARTÃO

portes grátis

 To date, processing of high-throughput Mass Spectrometry (MS) data is accomplished using serial algorithms. Developing new methods to process MS data is an active area of research but there is no single strategy that focuses on scalability of MS based methods.
INGLÊS

Sequence Analysis And Modern C++ - The Creation Of The Seqan3 Bioinformatics Library

de Hannes Hauswedell

189,25€ + 10% EM CARTÃO

portes grátis

 This is a book about software engineering, bioinformatics, the C++ programming language and the SeqAn library.
INGLÊS

High-Performance Algorithms For Mass Spectrometry-Based Omics

de Fahad Saeed e Muhammad Haseeb

118,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 To date, processing of high-throughput Mass Spectrometry (MS) data is accomplished using serial algorithms. Developing new methods to process MS data is an active area of research but there is no single strategy that focuses on scalability of MS based methods.
INGLÊS

Algorithms And Methods In Structural Bioinformatics

118,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved.<div><br><div>In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.</div></div>
INGLÊS

Land Use Cover Datasets And Validation Tools - Validation Practices With Qgis

47,30€ + 10% EM CARTÃO

portes grátis

 This open access book represents a comprehensive review of available land-use cover data and techniques to validate and analyze this type of spatial information.
INGLÊS

Sequence Analysis And Modern C++ - The Creation Of The Seqan3 Bioinformatics Library

de Hannes Hauswedell

184,84€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This is a book about software engineering, bioinformatics, the C++ programming language and the SeqAn library.
INGLÊS

Sequence Analysis And Modern C++ - The Creation Of The Seqan3 Bioinformatics Library

de Hannes Hauswedell

189,25€ + 10% EM CARTÃO

portes grátis

 This is a book about software engineering, bioinformatics, the C++ programming language and the SeqAn library.
INGLÊS

Adolescent Risk Behavior And Self-Regulation - A Cybernetic Perspective

de Franz Resch e Peter Parzer

148,70€ + 10% EM CARTÃO

portes grátis

 This book is based on the idea that increasing juvenile risk behaviours â€" like substance abuse, nonsuicidal self-injury, and antisocial or suicidal behaviour â€" allow adolescents to fulfill developmental tasks like identity-formation and regulation of self-worth.
INGLÊS

Networks In Systems Biology - Applications For Disease Modeling

162,21€ + 10% EM CARTÃO

portes grátis

 Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer.
INGLÊS

Networks In Systems Biology - Applications For Disease Modeling

162,21€ + 10% EM CARTÃO

portes grátis

 Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer.
INGLÊS

Advances In Artificial Intelligence, Computation, And Data Science - For Medicine And Life Science

211,34€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <p>Artificial intelligence (AI) has become pervasive in most areas of research and applications. While computation can significantly reduce mental efforts for complex problem solving, effective computer algorithms allow continuous improvement of AI tools to handle complexity—in both time and memory requirements—for machine learning in large datasets. Meanwhile, data science is an evolving scientific discipline that strives to overcome the hindrance of traditional skills that are too limited to enable scientific discovery when leveraging research outcomes. Solutions to many problems in medicine and life science, which cannot be answered by these conventional approaches, are urgently needed for society.</p><p>This edited book attempts to report recent advances in the complementary domains of AI, computation, and data science with applications in medicine and life science. The benefits to the reader are manifold as researchers from similar or different fields can be aware of advanced developments and novel applications that can be useful for either immediate implementations or future scientific pursuit.</p><p><b>Features:</b></p><p></p><ul><li>Considers recent advances in AI, computation, and data science for solving complex problems in medicine, physiology, biology, chemistry, and biochemistry</li><li>Provides recent developments in three evolving key areas and their complementary combinations: AI, computation, and data science</li><li>Reports on applications in medicine and physiology, including cancer, neuroscience, and digital pathology</li><li>Examines applications in life science, including systems biology, biochemistry, and even food technology</li></ul><p></p>This unique book, representing research from a team of international contributors, has not only real utility in academia for those in the medical and life sciences communities, but also a much wider readership from industry, science, and other areas of technology and education. <br>
INGLÊS

Networks In Systems Biology - Applications For Disease Modeling

158,34€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer.
INGLÊS

Automated Reasoning For Systems Biology And Medicine

118,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <div>This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or "bugs"). </div>Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. <div>Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? </div>This book brings together leading researchers from a number of highly interdisciplinary areas, including: <div>· Parameter inference from time series </div><div>· Model selection </div><div>· Network structure identification </div><div>· Machine learning </div><div>· Systems medicine </div><div>· Hypothesis generation from experimental data </div><div>· Systems biology, systems medicine, and digital pathology </div><div>· Verification of biomedical devices </div><div><br></div><div><div>"This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data."</div><div><i>Prof Luca Cardelli FRS, University of Oxford</i></div></div><div><br></div>
INGLÊS

Bioinformatics And Phylogenetics - Seminal Contributions Of Bernard Moret

131,84€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <p>This volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest.</p>Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelihood phylogeny estimation problem; describes the inference of species trees, covering strategies to scale phylogeny estimation methods to large datasets, and the construction of taxonomic supertrees; discusses the inference of ultrametric distances from additive distance matrices, and the inference of ancestral genomes under genome rearrangement events; reviews different techniques for inferring evolutionary histories in cancer, from the use of chromosomal rearrangements to tumor phylogenetics approaches; examines problems in phylogenetic networks, including questions relating to discrete mathematics, and issues of statistical estimation; highlights how evolution can provide a framework within which to understand comparative and functional genomics; provides an introduction to Integer Linear Programming and its use in computational biology, including its use for solving the Traveling Salesman Problem.<p></p><p></p><p></p><p>Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.</p><div><ul> </ul></div>
INGLÊS

Literary Modernism, Queer Temporality - Eddies In Time

de Kate Haffey

101,38€ + 10% EM CARTÃO

portes grátis

 By reading a series of early twentieth-century literary texts from modernists like Woolf, Eliot, Faulkner, and Stein alongside contemporary authors, this book examines the way in which modernist writers challenged narrative conventions of time in ways that both illuminate and foreshadow current scholarship on queer temporality.
INGLÊS

Phenotypes And Genotypes - The Search For Influential Genes

de David Ramsey, Florian Frommlet e Malgorzata Bogdan

121,66€ + 10% EM CARTÃO

portes grátis

 Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes).
INGLÊS

Introduction To Evolutionary Genomics

de Naruya Saitou

72,86€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book describes core processes of replication, mutation, neutral evolution and natural selection, genome evolution in prokaryotes, eukaryotes, vertebrates and humans, genome sequencing amd more, offering worked-out examples and extensive appendices.
INGLÊS

Scalable Big Data Analytics For Protein Bioinformatics - Efficient Computational Solutions For Protein Structures

de Dariusz Mrozek

118,59€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <div><div>This book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels and for prediction of 3D structures of proteins. Emphasis is placed on techniques that can be used to accelerate similarity searches and protein structure modeling processes.</div><div><br></div><div>The content of the book is divided into four parts. The first part provides background information on proteins and their representation levels, including a formal model of a 3D protein structure used in computational processes, and a brief overview of the technologies used in the solutions presented in the book. The second part of the book discusses Cloud services that are utilized in the development of scalable and reliable cloud applications for 3D protein structure similarity searching and protein structure prediction. The third part of the book shows the utilization of scalable Big Datacomputational frameworks, like Hadoop and Spark, in massive 3D protein structure alignments and identification of intrinsically disordered regions in protein structures. The fourth part of the book focuses on finding 3D protein structure similarities, accelerated with the use of GPUs and the use of multithreading and relational databases for efficient approximate searching on protein secondary structures.</div><div><br></div><div>The book introduces advanced techniques and computational architectures that benefit from recent achievements in the field of computing and parallelism. Recent developments in computer science have allowed algorithms previously considered too time-consuming to now be efficiently used for applications in bioinformatics and the life sciences. Given its depth of coverage, the book will be of interest to researchers and software developers working in the fields of structural bioinformatics and biomedical databases.</div></div><div><br></div>
INGLÊS

Guide To Cisco Routers Configuration - Becoming A Router Geek

de Mohammed M. Alani

60,82€ + 10% EM CARTÃO

portes grátis

 This easy-to-follow text/reference presents a practical guide to the configuration of Cisco routers, from tasks for beginners to advanced operations.
INGLÊS

Summarizing Biological Networks

de Boon-Siew Seah e Sourav S. Bhowmick

135,18€ + 10% EM CARTÃO

portes grátis

 Specifically, it discusses an array of techniques related to biological network clustering, network summarization, and differential network analysis which enable readers to uncover the functional and topological organization hidden in a large biological network.
INGLÊS

Theoretical And Applied Aspects Of Systems Biology

111,96€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases.
INGLÊS

Parameter Advising For Multiple Sequence Alignment

de Dan Deblasio e John Kececioglu

59,61€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 <p>This book develops a new approach called <i>parameter advising</i> for finding a parameter setting for a sequence aligner that yields a quality alignment of a given set of input sequences. In this framework, a parameter<i> advisor</i> is a procedure that automatically chooses a parameter setting for the input, and has two main ingredients:</p> <p>(a) the <i>set </i>of parameter choices considered by the advisor, and</p> <p>(b) an <i>estimator</i> of alignment accuracy used to rank alignments produced by the aligner.</p> <p>On coupling a parameter advisor with an aligner, once the advisor is trained in a learning phase, the user simply inputs sequences to align, and receives an output alignment from the aligner, where the advisor has automatically selected the parameter setting.</p> <p>The chapters first lay out the foundations of parameter advising, and then cover applications and extensions of advising. The content</p> <p>• examines formulations of parameter advising and their <i>computational complexity</i>,</p> <p>• develops methods for learning good <i>accuracy estimators</i>,</p> <p>• presents approximation algorithms for finding good sets of <i>parameter choices</i>, and </p> <p>• assesses <i>software implementations</i> of advising that perform well on real biological data.</p> <p>Also explored are applications of parameter advising to</p> <p>• <i>adaptive local realignment</i>, where advising is performed on local regions of the sequences to automatically adapt to varying mutation rates, and</p> <p>• <i>ensemble alignment</i>, where advising is applied to an ensemble of aligners to effectively yield a new aligner of higher quality than the individual aligners in the ensemble.</p> <p>The book concludes by offering future directions in advising research.</p>
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