Resultados de Pesquisa

INGLÊS

Asymmetric Cell Division In Development, Differentiation And Cancer

216,29€ + 10% EM CARTÃO

portes grátis

 Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth.
INGLÊS

Monocytes And Macrophages In Development, Regeneration, And Disease

~~264,34€~~ 237,91€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: "Macrophages - Origin, Functions and Biointervention" published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:<ul><li>Part I Nonimmunologic and immunologic functions of monocytes/macrophages</li><li>Part II Tissue/organ specific functions of macrophages</li><li>Part III Macrophage functions and dysfunction in diseases</li></ul>This book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages.
INGLÊS

Intercellular And Interorganellar Transfer And Communication In Biology And Medicine

~~330,59€~~ 297,53€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases.
INGLÊS

Syncytia: Origin, Structure, And Functions

216,29€ + 10% EM CARTÃO

portes grátis

 This book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis.
INGLÊS

Molecular Basis Of Developmental And Stem Cell Regulation - Classical Models Revised

de Hisato Kondoh

~~145,09€~~ 116,07€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This book provides a comprehensive overview of the molecular basis of developmental and stem cell regulation. It revisits some of the classical models of developmental biology and puts them in context with the findings of modern stem cell research and developmental biology. Biomedical research is embarking on a new era due to new tools, which are exemplified by stem cell technologies, single-cell transcriptome analysis, and live imaging at a single-cell resolution. Publications based on cutting-edge technologies do often not provide the readers with deep biological backgrounds. This causes the risk that precious data are reduced to highly specific descriptions without sufficient biological contexts.Contemporary developmental biology on the other hand as written in many textbooks, is to a significant extent based on conceptions backdated many decades ago, and is not necessarily supported by recent findings. Yet, the prevailing classical notions tend to mislead modern biomedical researches.This book not only presents current models for developmental processes but also reinterprets and re-evaluates classic observations, thus linking classical and modern worlds of developmental biology. Spanning from molecular mechanisms to highly embryological matters it provides a bridge between these different disciplines.Written for advanced students of developmental and stem cell biology, researchers and teaching scholars, this book provides a new road map to modern developmental biology and stem cell biology.
INGLÊS

Syncytia: Origin, Structure, And Functions

~~211,99€~~ 169,59€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis.
INGLÊS

Nuclear, Chromosomal, And Genomic Architecture In Biology And Medicine

~~264,34€~~ 211,47€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This volume reviews the latest research on the functional implications of nuclear, chromosomal and genomic organization and architecture on cell and organismal biology, and development and progression of diseases.The architecture of the cell nucleus and non-random arrangement of chromosomes, genes, and the non-membranous nuclear bodies in the three-dimensional (3D) space alters in response to the environmental, mechanical, chemical, and temporal cues. The changes in the nuclear, chromosomal, or genomic compaction and configuration modify the gene expression program and induce or inhibit epigenetic modifications. The intrinsically programmed rearrangements of the nuclear architecture are necessary for cell differentiation, the establishment of cell fate during development and maturation of tissues and organs including the immune, muscle, and nervous systems.The non-programmed changes in the nuclear architecture can lead to fragmentation of the nucleus and instability ofthe genome and thus cause cancer. Microbial and viral infections can lead to a clustering of centromeres, telomeres and ribosomal DNA and alter the properties of the nuclear membrane, allowing large immobile macromolecules to enter the nucleus. Recent advances in next-generation sequencing technologies combined with nucleus/chromosome conformation capture, super-resolution imaging, chromosomal contact maps methods, integrative modeling, and genetic approaches, are uncovering novel features and importance of nuclear, chromosomal and genomic architecture. This book is an interesting read for cell biologists, researchers studying the structure and function of chromosomes, and anyone else who wants to get an overview of the field of nuclear, chromosomal and genomic architecture.<div> </div>
INGLÊS

Bacterial Pathogens And Their Virulence Factors

de Douglas I. Johnson

121,66€ + 10% EM CARTÃO

portes grátis

 Bacterial Pathogens and their Virulence Factors contains a detailed description of 32 major bacterial pathogens that affect human health and their associated virulence determinants.
INGLÊS

Kidney Development And Disease

243,33€ + 10% EM CARTÃO

portes grátis

 The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease.
INGLÊS

Symbiosis: Cellular, Molecular, Medical And Evolutionary Aspects

216,29€ + 10% EM CARTÃO

portes grátis

 The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.
INGLÊS

Evo-Devo: Non-Model Species In Cell And Developmental Biology

201,43€ + 10% EM CARTÃO

portes grátis

 Evolutionary developmental biology or evo-devo is a field of biological research that compares the underlying mechanisms of developmental processes in different organisms to infer the ancestral condition of these processes and elucidate how they have evolved.
INGLÊS

Symbiosis: Cellular, Molecular, Medical And Evolutionary Aspects

216,29€ + 10% EM CARTÃO

portes grátis

 The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.
INGLÊS

Symbiosis: Cellular, Molecular, Medical And Evolutionary Aspects

~~211,34€~~ 169,07€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.
INGLÊS

Golgi Apparatus And Centriole - Functions, Interactions And Role In Disease

~~290,84€~~ 232,67€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined.Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi-Centriole relationship may be important for directional protein transport, cell polarization and cell cycle progression. Current studies indicate that Golgi and centriole also participate in development and act as cellular and immunological sensors, and that their abnormalities lead to cell and developmental abnormalities, Alzheimer, cancer, variouslipid disorders and neurological and immunological diseases in humans. This volume combines the latest information on the structure, molecular composition, and roles of Golgi and centriole in various cellular functions and diseases. The better understanding of the Golgi-centriole interactions may lead to the development of novel therapies for the treatment of various diseases, including cancer.
INGLÊS

Evo-Devo: Non-Model Species In Cell And Developmental Biology

~~197,43€~~ 157,94€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 Evolutionary developmental biology or evo-devo is a field of biological research that compares the underlying mechanisms of developmental processes in different organisms to infer the ancestral condition of these processes and elucidate how they have evolved.
INGLÊS

Student Voice And Teacher Professional Development - Knowledge Exchange And Transformational Learning

de David Morris

60,82€ + 10% EM CARTÃO

portes grátis

 Building upon a research study whereby pupils instruct their teachers in the use of Information and Communication Technology (ICT), the author argues that using student voice in this way can result in transformational learning for all those involved.
INGLÊS

Road-Mapping English Medium Education In The Internationalised University

de Emma Dafouz e Ute Smit

74,34€ + 10% EM CARTÃO

portes grátis

 This book is the first to offer a conceptual framework of English-medium education that can be used across different international higher education (HE) contexts.
INGLÊS

Marine Organisms As Model Systems In Biology And Medicine

337,96€ + 10% EM CARTÃO

portes grátis

 This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research.
INGLÊS

Human Neural Stem Cells - From Generation To Differentiation And Application

148,70€ + 10% EM CARTÃO

portes grátis

 This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.
INGLÊS

Tctp/Tpt1 - Remodeling Signaling From Stem Cell To Disease

189,25€ + 10% EM CARTÃO

portes grátis

 This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development.
INGLÊS

Human Neural Stem Cells - From Generation To Differentiation And Application

~~145,09€~~ 116,07€ 20% IMEDIATO

DISPONIBILIDADE IMEDIATA

 This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.
INGLÊS

Molecular Mechanisms Of Cell Differentiation In Gonad Development

270,36€ + 10% EM CARTÃO

portes grátis

 This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. the role of microRNAs in cell differentiation during gonad development;
INGLÊS

Human Neural Stem Cells - From Generation To Differentiation And Application

202,77€ + 10% EM CARTÃO

portes grátis

 This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.
INGLÊS

Marine Organisms As Model Systems In Biology And Medicine

337,96€ + 10% EM CARTÃO

portes grátis

 This book highlights the potential advantages of using marine invertebrates like tunicates, echinoderms, sponges and cephalopods as models in both biological and medical research.
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