Resultados de Pesquisa

INGLÊS

Statistical Learning In Genetics - An Introduction Using R

de Daniel Sorensen

~~198,09€~~ 178,28€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 <span lang="EN-GB" style="mso-fareast-font-family: ''Times New Roman''; mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin; mso-font-kerning: 0pt; mso-ligatures: none; mso-ansi-language: EN-GB; mso-fareast-language: EN-IN;">This book provides an introduction to computer-based methods for the analysis of genomic data. Breakthroughs in molecular and computational biology have contributed to the emergence of vast data sets, where millions of genetic markers for each individual are coupled with medical records, generating an unparalleled resource for linking human genetic variation to human biology and disease. Similar developments have taken place in animal and plant breeding, where genetic marker information is combined with production traits. An important task for the statistical geneticist is to adapt, construct and implement models that can extract information from these large-scale data. An initial step is to understand the methodology that underlies the probability models and to learn the modern computer-intensive methods required for fitting these models. The objective of this book, suitable for readers who wish to develop analytic skills to perform genomic research, is to provide guidance to take this first step.<span lang="EN-GB" style="mso-fareast-font-family: ''Times New Roman''; mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin; mso-font-kerning: 0pt; mso-ligatures: none; mso-ansi-language: EN-GB; mso-fareast-language: EN-IN;">This book is addressed to numerate biologists who may lack the formal mathematical background of the professional statistician. For this reason, considerably more detailed explanations and derivations are offered. Examples are used profusely and a large proportion involves programming with the open-source package R. The code needed to solve the exercises is provided and it can be downloaded, allowing students to experiment by running the programs on their own computer.Part I presents methods of inference and computation that are appropriate for likelihood and Bayesian models. Part II discusses prediction for continuous and binary data using both frequentist and Bayesian approaches. Some of the models used for prediction are also used for gene discovery. The challenge is to find promising genes without incurring a large proportion of false positive results. Therefore, Part II includes a detour on the False Discovery Rate, assuming frequentist and Bayesian perspectives. The last chapter of Part II provides an overview of a selected number of non-parametric methods. Part III consists of exercises and their solutions. This second edition has benefited from many clarifications and extensions of themes discussed in the first edition.<span lang="EN-GB" style="font-size: 11.0pt; line-height: 107%; font-family: ''Calibri'',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: ''Times New Roman''; mso-hansi-theme-font: minor-latin; mso-bidi-theme-font: minor-latin; mso-ansi-language: EN-GB; mso-fareast-language: EN-IN; m...
INGLÊS

Statistical Modelling Of Survival Data With Random Effects - H-Likelihood Approach

de Il Do Ha, Jong-Hyeon Jeong e Youngjo Lee

133,84€ + 10% EM CARTÃO

portes grátis

 This book provides a groundbreaking introduction to the likelihood inference for correlated survival data via the hierarchical (or h-) likelihood in order to obtain the (marginal) likelihood and to address the computational difficulties in inferences and extensions.
INGLÊS

Estimating Presence And Abundance Of Closed Populations

de George A. F. Seber e Matthew R. Schofield

~~105,99€~~ 95,39€ 10% IMEDIATO

DISPONIBILIDADE IMEDIATA

 Effort data used for removals can also be used.A very important method for estimating abundance is the use of capture-recapture data collected discretely or continuously and can be analysed using both frequency and Bayesian methods.
INGLÊS

Estimating Presence And Abundance Of Closed Populations

de George A. F. Seber e Matthew R. Schofield

~~81,10€~~ 72,99€ 10% IMEDIATO

portes grátis

 Effort data used for removals can also be used.A very important method for estimating abundance is the use of capture-recapture data collected discretely or continuously and can be analysed using both frequency and Bayesian methods.
INGLÊS

Statistical Learning In Genetics - An Introduction Using R

de Daniel Sorensen

184,84€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 The MarkDown interface allows the students to implement the code on their own computer, contributing to a better understanding of the underlying theory. Part I presents methods of inference based on likelihood and Bayesian methods, including computational techniques for fitting likelihood and Bayesian models.
INGLÊS

Applied Multivariate Statistics With R

de Daniel Zelterman

106,80€ + 10% EM CARTÃO

portes grátis

 Now in its second edition, this book brings multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations.
INGLÊS

Applied Multivariate Statistics With R

de Daniel Zelterman

98,71€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Now in its second edition, this book brings multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations.
INGLÊS

Structural Dynamics - Vibrations And Systems

de Madhujit Mukhopadhyay

101,38€ + 10% EM CARTÃO

portes grátis

 This book introduces the theory of structural dynamics, with focus on civil engineering structures. The book is ideal as a text for advanced undergraduates or graduate students taking a first course in structural dynamics.
INGLÊS

Statistical Design And Analysis Of Biological Experiments

de Hans-Michael Kaltenbach

75,69€ + 10% EM CARTÃO

portes grátis

 This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research.
INGLÊS

Applying Quantitative Bias Analysis To Epidemiologic Data

de Matthew P. Fox, Richard F. Maclehose e Timothy L. Lash

58,29€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This textbook and guide focuses on methodologies for bias analysis in epidemiology and public health, not only providing updates to the first edition but also further developing methods and adding new advanced methods.As computational power available to analysts has improved and epidemiologic problems have become more advanced, missing data, Bayes, and empirical methods have become more commonly used. This new edition features updated examples throughout and adds coverage addressing:<ul> <li>Measurement error pertaining to continuous and polytomous variables</li> <li>Methods surrounding person-time (rate) data</li> <li>Bias analysis using missing data, empirical (likelihood), and Bayes methods</li> </ul> A unique feature of this revision is its section on best practices for implementing, presenting, and interpreting bias analyses. Pedagogically, the text guides students and professionals through the planning stages of bias analysis, including the design of validation studies and the collection of validity data from other sources. Three chapters present methods for corrections to address selection bias, uncontrolled confounding, and measurement errors, and subsequent sections extend these methods to probabilistic bias analysis, missing data methods, likelihood-based approaches, Bayesian methods, and best practices.
INGLÊS

Innovations For Metropolitan Areas - Intelligent Solutions For Mobility, Logistics And Infrastructure Designed For Citizens

67,58€ + 10% EM CARTÃO

portes grátis

 This book presents human-centered concepts and solutions for mobility, logistics and infrastructure that will make our growing metropolitan areas more livable and sustainable.The still accelerating megatrend of urbanization is leading to constantly growing metropolitan areas.
INGLÊS

Advances In Polymer Processing 2020 - Proceedings Of The International Symposium On Plastics Technology

189,25€ + 10% EM CARTÃO

portes grátis

 This book gathers the proceedings of the International Symposium on Plastics Technology, which was held on March 10, 2020 in Aachen, Germany, and was organised by the Institute for Plastics Processing (IKV) in Industry and Craft at RWTH Aachen University.
INGLÊS

Nile Water Rights - An International Law Perspective

de Philine Wehling

121,66€ + 10% EM CARTÃO

portes grátis

 The book provides a comprehensive assessment of the law governing the use and management of the Nile and considers, more broadly, how international water law can guide the development of a legal and institutional framework for cooperation over shared freshwater resources.
INGLÊS

Likelihood And Bayesian Inference - With Applications In Biology And Medicine

de Daniel Sabanes Bove e Leonhard Held

51,36€ + 10% EM CARTÃO

portes grátis

 Topics include Bayesian updating, conjugate and reference priors, Bayesian point and interval estimates, Bayesian asymptotics and empirical Bayes methods.
INGLÊS

Mathematical Reasoning Of Children And Adults - Teaching And Learning From An Interdisciplinary Perspective

202,77€ + 10% EM CARTÃO

portes grátis

 This book adopts an interdisciplinary approach to investigate the development of mathematical reasoning in both children and adults and to show how understanding the learnerâ€™s cognitive processes can help teachers develop better strategies to teach mathematics.
INGLÊS

Statistical Design And Analysis Of Biological Experiments

de Hans-Michael Kaltenbach

148,70€ + 10% EM CARTÃO

portes grátis

 This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research.
INGLÊS

Analytic Combinatorics For Multiple Object Tracking

de Murat Efe, Robert Blair Angle e Roy Streit

148,70€ + 10% EM CARTÃO

portes grátis

 Since GFs are not widely utilized amongst the tracking community, the book takes the reader from the basics of the subject to applications of theory starting from the simplest problem of single object tracking, and advancing chapter by chapter to more challenging multi-object tracking problems.
INGLÊS

Bioactive Molecules In Plant Defense - Saponins

de Mostafa Abdelrahman e Sudisha Jogaiah

162,21€ + 10% EM CARTÃO

portes grátis

 This book presents a broad perspective on saponins as important natural products with a key role in plant defense.
INGLÊS

Public Reason And Bioethics - Three Perspectives

162,21€ + 10% EM CARTÃO

portes grátis

 This book explores and elaborates three theories of public reason, drawn from Rawlsian political liberalism, natural law theory, and Confucianism.
INGLÊS

Education Reform In The Twenty-First Century - The Marketization Of Teaching And Learning At A No-Excuses Charter School

de Erinn Brooks

121,66€ + 10% EM CARTÃO

portes grátis

 This book explores how, why, and with what consequences one no-excuses charter network marketizes teaching and learning, through the authorâ€™s 1000 hours of covert participant observation at a network charter school.
INGLÊS

Pilot Society And The Energy Transition - The Co-Shaping Of Innovation, Participation And Politics

de Marianne Ryghaug e Tomas Moe Skjã¸Lsvold

33,79€ + 10% EM CARTÃO

portes grátis

 This open access book examines the role of pilot and demonstration projects as crucial devices for conducting innovation in the context of the energy transition.
INGLÊS

Statistical Design And Analysis Of Biological Experiments

de Hans-Michael Kaltenbach

98,71€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research.
INGLÊS

Heterogeneity In Statistical Genetics - How To Assess, Address, And Account For Mixtures In Association Studies

de Derek Gordon, Stephen J. Finch e Wonkuk Kim

139,79€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.We anticipate that this book will be useful to researchers who want to estimate heterogeneity in their data, develop or apply genetic association statistics where heterogeneity exists, and accurately evaluate statistical power and sample size for genetic association through the application of robust experimental design.
INGLÊS

Meta-Analysis - Methods For Health And Experimental Studies

de Shahjahan Khan

59,61€ + 10% EM CARTÃO

DISPONIBILIDADE IMEDIATA

 This book focuses on performing hands-on meta-analysis using MetaXL, a free add-on to MS Excel. The illustrative examples are taken mainly from medical and health sciences studies, but the generic methods can be used to perform meta-analysis on data from any other discipline. The book adopts a step-by-step approach to perform meta-analyses and interpret the results. Stata codes for meta-analyses are also provided.All popularly used meta-analytic methods and models - such as the fixed effect model, random effects model, inverse variance heterogeneity model, and quality effect model - are used to find the confidence interval for the effect size measure of independent primary studies and the pooled study. In addition to the commonly used meta-analytic methods for various effect size measures, the book includes special topics such as meta-regression, dose-response meta-analysis, and publication bias.The main attraction for readers is the book’s simplicity and straightforwardness in conducting actual meta-analysis using MetaXL. Researchers would easily find everything on meta-analysis of any particular effect size in one specific chapter once they could determine the underlying effect measure. Readers will be able to see the results under different models and also will be able to select the correct model to obtain accurate results.
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