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Vegf And Cancer

97,34€ + 10% CARD

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 A comprehensive review of knowledge on the role of vascular endothelial growth factor (VEGF) in cancer. This work includes features such as: discussion of VEGF as potent angiogenic factor and its role in tumor angiogenesis; review of the biology, molecular properties and regulation of VEGF; and more.
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Genetic Mechanisms In Multiple Endocrine Neoplasia Type 2

59,61€ + 10% CARD

 This book examines what is known about the molecular biology of multiple endocrine neoplasia, type 2 (MEN2). Mutations and alterations in gene expressions and signal transduction are placed in the context of their effects on the biology of the thyroid and adrenal cells which generate cancers in MEN2. Thus, this volume addresses the ret mutations, the effects these mutations may have on signal transduction, and developmental and neurobiological aspects of the cells affected of MEN2, and provides the basic researcher - in genetics, signal transduction, cell transformation, developmental or neurobiology - with a better understanding of how the knowledge generated by each of these fields intercalates within the overall biology of MEN2.
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Glycoproteins And Human Disease

by Inka Brockhausen e William Kuhns

118,59€ + 10% CARD

 Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically.
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Human Hematopoiesis In Scid Mice

118,59€ + 10% CARD

 This monograph presents information on the use of the immunodeficient CB-17 SCID mouse for studying human haematopoiesis in vivo. Due to the lack of both humoral and cellular immunity, this mouse is a unique host for implantation of human haemotopoietic tissue.
ENGLISH

Intracellular Parasitism Of Microorganisms

by Yuri F. Belyi

59,61€ + 10% CARD

 This book is about mechanisms of intracellular parasitism of Legionella, Listeria and Mycobacterium. The presented data illustrate the hypothesis that one of the ways by which intracellularly multiplying bacteria influence the bactericidal response of phagocytes is by altering signaling cascades in eukaryotes. To achieve this goal bacteria are capable to produce enzymes and other biologically active compounds which misdirect signaling pathways for the benefit of the parasites. The book is composed of two main parts. The first provides general information on signaling cascades in eukaryotic cells. Analysis of Legionella, Listeria and Mycobacterium products possessing regulatory activity toward metabolism of host cells, essentially by affecting signal transduction in eukaryotes, is performed in the second section.
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Local Immunosuppression Of Organ Transplants

59,61€ + 10% CARD

 For the first time a complete review of the research work done over the past 30 years by leading investigators around the world in targeting immunosuppressants to both solid-organ and cellular transplants is available in a single volume. One section consists of studies conducted in rat allograft models using osmotic minipumps for delivery of a variety of immunosuppressants. The book will be of great benefit to researchers in the fields of transplant immunology, pharmacology and drug delivery and targeting, particularly those involved in drug development.
ENGLISH

Molecular Biology Of Cardiac Development And Growth

59,61€ + 10% CARD

 This book is concerned with basic molecular biology and how research in this field relates to our understanding of molecular and cellular aspects of cardiac development and growth. The authors point out that molecular biology has provided a wealth of new approaches for investigating cellular processes at the molecular level and is now making a significant contribution to the understanding of the molecular mechanisms underlying cardiac development and providing insight into the molecular events underlying cardiac malformation and disease. This volume combines basic information on molecular biology with current thinking in cardiac development. It is the only book to specifically do this.
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Monoclonal Antibodies In Transplantation

59,61€ + 10% CARD

 Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection.
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Myocardial Preconditioning

118,59€ + 10% CARD

 This work examines myocardial preconditioning, the ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium. It describes features and characteristics with respect to the time-course of the protective effect of the phenomenon.
ENGLISH

Protein And Amino Acid Metabolism In Cancer Cachexia

131,84€ + 10% CARD

 Cancer cachexia is a complex syndrome characterized by diminished nutrient intake and progressive tissue depletion manifest clinically as anorexia and weight loss.
ENGLISH

Signal Transduction And Bacterial Virulence

59,61€ + 10% CARD

 In order to survive, bacteria must constantly monitor their structure and physiology. The purpose of this volume is to give an overview of the various systems and to introduce recent advances in understanding selected systems of pathogenic bacteria.
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Spontaneous And Induced Intima Formation In Blood Vessels

by Mark M. Kockx

118,59€ + 10% CARD

 Atherosclerosis, the most common disease in humans and also the main cause of death in the Western world, only develops after an intima is formed. The intima is defined as the region of the arterial wall from the endothelial surface to the luminal margin of the media. <BR>This volume considers all aspects of intima formation based on results which had been obtained by studying three different models: <BR>- Spontaneous intima formation; <BR>- Experimentally induced intima formation; <BR>- Latrogeneously induced intima formation.
ENGLISH

Immune Functions Of Epidermal Langerhans Cells

59,61€ + 10% CARD

 This book is about the phenotypic and functional features of epidermal Langerhans cells in experimental models and in clinical medicine. Langerhans cells, members of the dendritic cell system in the skin, are critically involved in the regulation of cell-mediated immune responses and gain increasing attention in a wide spectrum of clinical areas such as allergy, autoimmunity, transplantation and resistance to tumors and infections. The book covers the latest, most timely developments in this rapidly advancing field. Leading researchers describe functional analyses at the cell and molecular level, elucidating processes related to antigen presentation and the role of cytokines, and discuss perspectives for a future use of Langerhans cells and other dendritic cells in the immunotherapy of various diseases.
ENGLISH

Molecular Biology Of Paget'S Disease

59,61€ + 10% CARD

 This work ssummarizes the molecular and cellular aspects of Paget's disease, a bone disease which is thought to be caused by a viral infection, and can occasionally lead to such fatal complications as osteosarcoma.
ENGLISH

C-Myc Function In Neoplasia

by C.V. Dang e Linda A. Lee

118,59€ + 10% CARD

 This text provides an overview of signal transduction and the biology of cell proliferation as a background for a review of the c-Myc oncogene and its protein product. Since c-Myc altered expression is involved in many human cancers, the chapters aim to reveal the function of c-Myc in neoplasia.
ENGLISH

Clinical Benefits Of Leukodepleted Blood Products

59,61€ + 10% CARD

 Provides a state-of-the-art description of the current status of leukodepleted blood products. Advances in technology, particularly filtration, have achieved great success in the selective removal of these white cells, and this book examines the benefits of such blood products.
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The Posterior Intrahepatic Approach In Liver Surgery

121,66€ + 10% CARD

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 The objective of The Posterior Intrahepatic Approach in Liver Surgery is to describe techniques, as the more routine application today of split liver, living donor transplantation has continued to teach us more about the anatomy of the liver and its applications.
ENGLISH

New Bacterial Vaccines

118,59€ + 10% CARD

 New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The distinctive feature of this book is that it focuses upon new vaccines now under development by reviewing key issues for each vaccine target and new technologies being applied to developing new vaccines.
ENGLISH

Hematopoietic Stem Cell Development

171,59€ + 10% CARD

 Collects articles on the biology of hematopoietic stem cells during embryonic development, reporting on fly, fish, avian and mammalian models. This book offers a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing conserved trends in development. It reviews knowledge on human hematopoietic development.
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Rb And Tumorigenesis

175,73€ + 10% CARD

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 Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.
ENGLISH

Molecular Mechanisms Of Phagocytosis

175,73€ + 10% CARD

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 Although, Phagocytosis was first described nearly 120 year ago, we are just recently beginning to understand the molecules that phagocytic cells use to bring about this complex cell function.
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The Posterior Intrahepatic Approach In Liver Surgery

121,66€ + 10% CARD

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 The objective of The Posterior Intrahepatic Approach in Liver Surgery is to describe techniques, as the more routine application today of split liver, living donor transplantation has continued to teach us more about the anatomy of the liver and its applications.
ENGLISH

Immunogenetics Of Autoimmune Disease

171,59€ + 10% CARD

 Based on a disease by disease approach, this book summarizes the knowledge in the field of immunogenetics covering a variety of topics relating to autoimmune diseases.
ENGLISH

Immunology Of Pregnancy

237,84€ + 10% CARD

 Covers contemporary hypotheses and studies related to the immunology of implantation. This book provides a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR.
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