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Molecular Biology Of Aging

171,59€ + 10% CARD

 Proceedings of a symposium held at the Brookhaven National Laboratory, Upton, New York, September 30-October 1, 1984
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Computational Approaches In Molecular Radiation Biology - Monte Carlo Methods

171,59€ + 10% CARD

 Proceedings of a DOE Workshop held in Irvine, California, April 26-29, 1993
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Biology Of Adventitious Root Formation

237,84€ + 10% CARD

 Charles E. Hess Department of Environmental Horticulture University of California Davis, CA 95616 Research in the biology of adventitious root formation has a special place in science. It provides an excellent forum in which to pursue fundamental research on the regulation of plant growth and development. At the same time the results of the research have been quickly applied by commercial plant propagators, agronomists, foresters and horticulturists (see the chapter by Kovar and Kuchenbuch, by Ritchie, and by Davies and coworkers in this volume). In an era when there is great interest in speeding technology transfer, the experiences gained in research in adventitious root formation may provide useful examples for other areas of science. Interaction between the fundamental and the applied have been and continue to be facilitated by the establishment, in 1951, of the Plant Propagators' Society, which has evolved into the International Plant Propagators' Society, with active programs in six regions around the world. It is a unique organization which brings together researchers in universities, botanical gardens and arboreta, and commercial plant propagators. In this synergistic environment new knowledge is rapidly transferred and new ideas for fundamental research evolve from the presentations and discussions by experienced plant propagators. In the past 50 years, based on research related to the biology of adventitious root formation, advances in plant propagation have been made on two major fronts.
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Photosynthetic Carbon Assimilation

59,61€ + 10% CARD

 The photosynthetic fixation of carbon dioxide into organic compounds is mediated by the enzyme ribulose 1,S-bisphosphate (RuBP) carboxylase. The diversity of current research on this protein attests to its central role in biomass productivity, and suggests the importance of a timely and broadly based review. This Symposium was the first devoted exclusively to RuBP carboxylase and was attended by agronomists, plant physiologists, biochemists, molecular biologists, and crystallographers. Special efforts were made to involve young scientists in addition to established investigators. It is a pleasure to acknowledge financial support provided by the Department of Energy, the United States Department of Agricul ture, and the National Science Foundation, and the valued assistance of agency representatives, Drs. Joe Key, Robert Rabson, Elijah Romanoff, and Donald Senich. Thanks are due to Mrs. Margaret Dienes, without whose editorial skills this volume could not have been produced, and to Mrs. Helen Kondratuk as Symposium Coordinator. Finally, we wish to record our indebtedness to Dr. Alexander Hollaender for his tireless efforts in support of all aspects of this Symposium.
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Physical And Chemical Mechanisms In Molecular Radiation Biology

59,61€ + 10% CARD

 Proceedings of a Workshop held at the National Academy of Sciences Study Center, Woods Hole, Massachusetts, September 3-6, 1990
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Nmr Applications In Biopolymers

118,59€ + 10% CARD

 Proceedings based on an American Chemical Society symposium held in Los Angeles, California, September 25--28, 1988, and an ACS symposium held in Toronto, Canada, June 5--8, 1988
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Neutron Beam Design, Development, And Performance For Neutron Capture Therapy

118,59€ + 10% CARD

 Proceedings of an International Workshop held at the Massachusetts Institute of Technology, in Cambridge, Massachusetts, March 29-31, 1989
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Clinical Aspects Of Neutron Capture Therapy

118,59€ + 10% CARD

 Since Locher first suggested Boron Neutron Capture Therapy (BNCT) in 1936, this theoretically ideal system has intrigued investigators. Unfortunately, the first clinical trials between 1951-1961 were not successful. However, they served to implant firmly the seed of BNCT, the growth of which has been carefully nurtured at a number of locations world-wide. This fact is attested to by the ongoing clinical trials in Japan as well as by the presence of researchers from active groups in the ten countries represented at this Workshop. In 1983 and 1985, the first and second international biannual symposia on BNCT were held, in response to a resurgence of interest in this field. In 1986, the DOE sponsored a workshop on NCT, in large part directed toward evaluating the national effort and the various neutron sources available within the United States. It now seems likely, because of various factors including improved neutron beams and boron delivery systems which have made the modality more attractive, that clinical trials will be initiated in the United States within the next few years. This 1988 special workshop, interspersed between the biannual international symposia, represents an effort to seek ideas and advice on the clinical a~pects of BNCT, from all those diverse groups with a national commitment to this project. Our purpose is to facilitate our endeavor to incorporate the best procedures and techniques in the upcoming clinical trials.
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Phenotypic Variation In Populations - Relevance To Risk Assessment

118,59€ + 10% CARD

 The human race has enormous he terogenei ty, founded on genetic and environmental sources. Variability, therefore, is a vital dimension in any consideration of human risk assessment. In the estimation of risks, current methods of extrapolation based upon converting the response of a median man are inadequate, as they ignore phenotypic variation and there fore, susceptible subgroups. There is a growing literature defining the extent of human variation in normal populations; thus, the normal young adult population may have 10-20% known hyperreactors. How far can we ignore human variability in risk assessment? Should we be concerned with susceptible groups, and how can we modify the risk assessment analysis accordingly? The aim of our meeting was to bring together experts from the fields of human epidemiology, toxicology, aging, genetics, carcino genesis and teratology, and to provide a forum in which we might assimi late knowledge of human heterogeneity as a coherent whole. Since the resolution and obligations of risk assessment, in the last analysis, are a political process, we also involved representatives from the legal field, the unions, and the regulatory agencies. We are most grateful for financial support from the National Institute on Aging; the u. S. Environmental Protection Agency; the U. S. Department of Energy; FDA - National Center for Toxicological Research; The Council for Tobacco Research-USA, Inc; Johnson and Johnson; Merck Sharp and Dohme Research Laboratories; and Associated Universities, Inc. We thank our Symposium Coordinator, Ms.
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Genetic Engineering Of Animals - An Agricultural Perspective

59,61€ + 10% CARD

 J. Warren Evans Department of Animal Science Texas A&M University College Station, Texas 77843 In the near future, improvement of domestic animals for the production of food and fiber is poised to undergo a revolution by the utilization of recent breakthroughs and advances in molecular genetics, embryo manipula tions, and gene transfer systems. Utilization of these techniques will have a wide impact on animal agriculture by improvement of production effi ciency via manipulation and control of many physiological systems. The end result will be to decrease production costs, increase food production and quality, and lower food costs. Health and well being of domestic and other animals will be improved as a result of new methods of disease diagnosis, vaccine production, and disease prevention practices. Genetic engineering also offers the possibility of utilizing animals for the development of pharmaceutical products to benefit society. Research progress will be en hanced via manipulation of the gene pool. The objectives of this Conference were to discuss the current status of animal bioengineering and to realistically assess the potential applica tions of current and future genetic technologies for the production of food and fiber to meet the needs of our hungry world, and to provide animal sci entists who may wish to utilize bioengineering in current or future re search programs with current background information regarding concepts, ap plications, and methodologies.
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Assessment Of Risk From Low-Level Exposure To Radiation And Chemicals - A Critical Overview

118,59€ + 10% CARD

 A Critical Overview.
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Sister Chromatid Exchanges - 25 Years Of Experimental Research Part B Genetic Toxicology And Human Studies

59,61€ + 10% CARD

 Chromosomes, being well-defined structures that are easily vis- ible under the optical microscope, readily lend themselves to in- tense physical and biochemical study. One of the most important stages in chromosome research was the development, in radiation biology, of radiolabeling the chromosome with tritiated thymidine.
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Genetic Control Of Environmental Pollutants

by Alexander Hollaender, Claire M. Wilson e Gilbert S. Omenn

59,61€ + 10% CARD

 Omenn Dean, Public Health and Community Medicine University of Washington Seattle, Washington 98195 On behalf of the University of Washington, the City of Seattle, the sponsors and donors, and my co-organizers, I am delighted to welcome all of you to this Conference on Genetic Control of Environ- mental Pollutants.
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Genetic Engineering Of Plants - An Agricultural Perspective

by Alexander Hollaender, Carole P. Meredith, Claire M. Wilson e Tsune Kosuge

118,59€ + 10% CARD

 An Agricultural Perspective.
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Basic Biology Of New Developments In Biotechnology

118,59€ + 10% CARD

 Laskin Biosciences Research Exxon Research and Engineering Company Linden, New Jersey I was contacted in the Fall of 1981 by Professors Martin Dworkin and Palmer Rogers, of the University of Minnesota and asked to participate in the orgnization of the 1983 conference in the series, "Interface Between Biology and Medicine".
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Organ And Species Specificity In Chemical Carcinogenesis

59,61€ + 10% CARD

 The Symposium on Organ and Species Specificity in Chemical Carcinogenesis was held March 1981 in Raleigh, North Carolina. We badly need an adequate data base on human organs, human tissues, human cells, human subcellular preparations, and human body fluids.
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Induced Mutagenesis - Molecular Mechanisms And Their Implications For Environmental Protection

59,61€ + 10% CARD

 The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results.
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Genetic Engineering Of Microorganisms For Chemicals

118,59€ + 10% CARD

 The resultant interaction should encourage new and extended ideas for the improve ment of strains and for the generation of new regulatory combina tions to enhance microbial chemical production from cheap and abundant (including waste) substrates.
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Trends In The Biology Of Fermentations For Fuels And Chemicals

118,59€ + 10% CARD

 The growing concern about where energy rich chemicals for the future will come from has stimulated a resurgence of interest in the potentialities of microbial fermentations to assist in meeting anti cipated demands for fuels and chemicals.
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Genetic Engineering Of Osmoregulation - Impact Of Plant Productivity For Food, Chemicals, And Energy

118,59€ + 10% CARD

 Impact of Plant Productivity for Food Chemicals and Energy.
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Molecular Mechanisms For Repair Of Dna - Part A

118,59€ + 10% CARD

 An "age" has passed in the 40 years since we first observed recovery from radiation damage in irradiated bacteria. During the early 1930s, we had been discussing the possibility of rapid changes after radiation exposure with Farring- ton Daniels, Benjamin Duggar, John Curtis, and others at the University of Wisconsin. After working with living cells, we had concluded that organisms receiving massive insults must have a wide variety of repair mechanisms available for restoration of at least some of the essential properties of the cell. The problem was how to fmd and identify these recovery phenomena. At that time I was working on a problem considered to be of great importance-the existence of the so-called mitogenetic rays. Several hundred articles and a score of books had already appeared dealing with mitogenetic rays, a type of radiation that was thought to exist in the shorter ultraviolet region. Our search for mitogenetic rays necessitated the design of experiments of greatest sensitivity for the detection of ultraviolet. It was vital that conditions be kept as constant as possible during exposure. All the work was done at icewater temperature (3-5(deg)C) during and after exposure. We knew that light was an important factor for cell recovery, so all our experiments were done in dim light, with the plated-out cells being covered with dark cloth. Our statements on the effect of visible light stimulated Kelner to search for "photoreactivation' (as it was later called).
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Physiology And Genetics Of Reproduction - Part B

118,59€ + 10% CARD

 Part B.
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Genetic Diversity In Plants

118,59€ + 10% CARD

 For the last eighteen years we have been deeply involved in a cooperative effort with our Latin American colleagues in genetics, biochemistry, physiology, and molecular biology. We have been in close contact with scientists in a number of centers and have helped to organize symposia, workshops, and so forth, in an effort to accelerate their development and make their substantial work known. These symposia in Latin America have been quite successful. The fifteenth will take place in Brasilia in 1977. At the request of colleagues, we are in the process of developing a similar series in Asia. The first very successful symposium was held in Calcutta in 1973. We were most pleased when Dr. Amir Muhammed, Vice Chancellor of the University of Agriculture, Lyallpur suggested that we hold a symposium on a topic of great importance to Pakistan, Genetic Control of Diversity in Plants, under the auspices of the University of Agriculture. It is our hope that this symposium will be followed by additional ones in Pakistan as well as in other countries in the Far East. Leadership is quickly developing in the hands of outstanding scientists in these countries, and we appreciate the opportunity to cooperate with them. We are especially grateful to the Natiohal Science Foundation for makingPL- 480 funds available which made this symposium possible.
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Genetic Engineering For Nitrogen Fixation

118,59€ + 10% CARD

 There is a time in scientific research when a number of developments coincide making it possible to progress with a tough and complicated problem. It is believed that such a time has come in the area of biological nitrogen fixation. A better understanding of photosynthesis, cell hybridization, plasmid, and gene transfer between cells not necessarily genetically related, have opened new avenues of research. New developments in traditional genetics, cell biology, biochemistry, including enzyme chemistry, and plant physi ology have brought about the feeling this is a most appro priate time to pull together the different approaches in a conference where the lines of research could be discussed and thus help to speed up developments in this area. What makes biological nitrogen fixation especially im portant is the promise that a good understanding of the basic problem would help us to make organisms more amenable to fix nitrogen, not only in symbiosis with legumes, but also with other plant species and develop a wider variety of organisms with the ability to fix N • It will also 2 encourage a search for naturally occurring N2 fixing organ isms other than the traditional N2 fixers. Some success has already been encountered in this area. Success in broadening the field of nitrogen fixing would help to increase food supply, especially in de veloping countries which cannot afford to purchase synthetic nitrogen sources.
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